IUBMB Enzyme Nomenclature


Accepted name: (3R,6E)-nerolidol synthase

Reaction: (2E,6E)-farnesyl diphosphate + H2O = (3R,6E)-nerolidol + diphosphate

For diagram of reaction click here.

Other name(s): terpene synthase 1

Systematic name: (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(3R,6E)-nerolidol-forming]

Comments: The enzyme catalyses a step in the formation of (3E)-4,8-dimethyl-1,3,7-nonatriene, a key signal molecule in induced plant defense mediated by the attraction of enemies of herbivores [1]. Nerolidol is a naturally occurring sesquiterpene found in the essential oils of many types of plants.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Schnee, C., Kollner, T.G., Gershenzon, J. and Degenhardt, J. The maize gene terpene synthase 1 encodes a sesquiterpene synthase catalyzing the formation of (E)-β-farnesene, (E)-nerolidol, and (E,E)-farnesol after herbivore damage. Plant Physiol. 130 (2002) 2049-2060. [PMID: 12481088]

[EC created 2010]

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