IUBMB Enzyme Nomenclature


Accepted name: β-phellandrene synthase (neryl-diphosphate-cyclizing)

Reaction: neryl diphosphate = β-phellandrene + diphosphate

Other name(s): phellandrene synthase 1; PHS1; monoterpene synthase PHS1

Systematic name: neryl-diphosphate diphosphate-lyase [cyclizing; β-phellandrene-forming]

Comments: The enzyme from Solanum lycopersicum has very poor affinity with geranyl diphosphate as substrate. Catalyses the formation of the acyclic myrcene and ocimene as major products in addition to β-phellandrene [1].

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Schilmiller, A.L., Schauvinhold, I., Larson, M., Xu, R., Charbonneau, A.L., Schmidt, A., Wilkerson, C., Last, R.L. and Pichersky, E. Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate. Proc. Natl. Acad. Sci. USA 106 (2009) 10865-10870. [PMID: 19487664]

[EC created 2010]

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