IUBMB Enzyme Nomenclature


Accepted name: valencene synthase

Reaction: (2E,6E)-farnesyl diphosphate = (+)-valencene + diphosphate

For diagram of reaction click here.

Systematic name: (2E,6E)-farnesyl-diphosphate diphosphate-lyase (valencene-forming)

Comments: The recombinant enzyme from Vitis vinifera gave 49.5% (+)-valencene and 35.5% (–)-7-epi-α-selinene. Initial cyclization gives (+)-germacrene A in an enzyme bound form which is not released to the medium.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Lucker, J., Bowen, P. and Bohlmann, J. Vitis vinifera terpenoid cyclases: functional identification of two sesquiterpene synthase cDNAs encoding (+)-valencene synthase and (–)-germacrene D synthase and expression of mono- and sesquiterpene synthases in grapevine flowers and berries. Phytochemistry 65 (2004) 2649-2659. [PMID: 15464152]

[EC created 2011]

Return to EC 4.2.3 home page
Return to EC 4.2 home page
Return to EC 4 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page