IUBMB Enzyme Nomenclature


Accepted name: (+)-δ-selinene synthase

Reaction: (2E,6E)-farnesyl diphosphate = (+)-δ-selinene + diphosphate

For diagram of reaction click here.

Glossary: (+)-δ-selinene = (4aR)-1,4a-dimethyl-7-(propan-2-yl)-2,3,4,4a,5,6-hexahydronaphthalene

Systematic name: (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-δ-selinene-forming]

Comments: Initial cyclization gives germacrene C in an enzyme bound form which is not released to the medium.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Steele, C.L., Crock, J., Bohlmann, J. and Croteau, R. Sesquiterpene synthases from grand fir (Abies grandis). Comparison of constitutive and wound-induced activities, and cDNA isolation, characterization, and bacterial expression of δ-selinene synthase and γ-humulene synthase. J. Biol. Chem. 273 (1998) 2078-2089. [PMID: 9442047]

2. Little, D.B. and Croteau, R.B. Alteration of product formation by directed mutagenesis and truncation of the multiple-product sesquiterpene synthases δ-selinene synthase and γ-humulene synthase. Arch. Biochem. Biophys. 402 (2002) 120-135. [PMID: 12051690]

[EC created 2011]

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