IUBMB Enzyme Nomenclature


Accepted name: thujopsene synthase

Reaction: (2E,6E)-farnesyl diphosphate = (+)-thujopsene + diphosphate

For diagram of reaction click here and mechanism click here.

Systematic name: (2E,6E)-farnesyl-diphosphate lyase (cyclizing, (+)-thujopsene-forming)

Comments: The recombinant enzyme from the plant Arabidopsis thaliana produces 27.3% (+)-α-barbatene, 17.8% (+)-thujopsene and 9.9% (+)-β-chamigrene [1] plus traces of other sesquiterpenoids [2]. See EC (+)-α-barbatene synthase, and EC β-chamigrene synthase.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Wu, S., Schoenbeck, M.A., Greenhagen, B.T., Takahashi, S., Lee, S., Coates, R.M. and Chappell, J. Surrogate splicing for functional analysis of sesquiterpene synthase genes. Plant Physiol. 138 (2005) 1322-1333. [PMID: 15965019]

2. Tholl, D., Chen, F., Petri, J., Gershenzon, J. and Pichersky, E. Two sesquiterpene synthases are responsible for the complex mixture of sesquiterpenes emitted from Arabidopsis flowers. Plant J. 42 (2005) 757-771. [PMID: 15918888]

[EC created 2011]

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