Reaction: (2E,6E)-farnesyl diphosphate = γ-curcumene + diphosphate
For diagram of reaction click here and mechanism click here.
Other name(s): PatTpsA (gene name)
Systematic name: (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, γ-curcumene-forming)
Comments: One of five sesquiterpenoid synthases in Pogostemon cablin (patchouli).
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:
References:
1. Deguerry, F., Pastore, L., Wu, S., Clark, A., Chappell, J. and Schalk, M. The diverse sesquiterpene profile of patchouli, Pogostemon cablin, is correlated with a limited number of sesquiterpene synthases. Arch. Biochem. Biophys. 454 (2006) 123-136. [PMID: 16970904]