IUBMB Enzyme Nomenclature


Accepted name: 3-aminobutyryl-CoA ammonia-lyase

Reaction: L-3-aminobutyryl-CoA = crotonoyl-CoA + NH3

For diagram of reaction click here.

Other name(s): L-3-aminobutyryl-CoA deaminase; L-3-aminobutyryl-CoA ammonia-lyase

Systematic name: L-3-aminobutyryl-CoA ammonia-lyase (crotonoyl-CoA-forming)

Comments: hydroxylamine can replace ammonia as a substrate. Crotonoyl-pantetheine can replace crotonoyl-CoA but it is a poorer substrate.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 55467-41-9


1. Jeng, I.-M., Barker, H.A. Purification and properties of L-3-aminobutyryl coenzyme A deaminase from a lysine-fermenting Clostridium. J. Biol. Chem. 249 (1974) 6578-6584. [PMID: 4420467]

2. Barker, H.A., Kahn, J.M., Chew, S. Enzymes involved in 3,5-diaminohexanoate degradation by Brevibacterium sp. J. Bacteriol. 143 (1980) 1165-1170. [PMID: 7410315]

[EC created 1999]

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