IUBMB Enzyme Nomenclature


Accepted name: erythro-3-hydroxy-L-aspartate ammonia-lyase

Reaction: erythro-3-hydroxy-L-aspartate = oxaloacetate + NH3

Other name(s): erythro-β-hydroxyaspartate dehydratase; erythro-3-hydroxyaspartate dehydratase; erythro-3-hydroxy-Ls-aspartate hydro-lyase (deaminating); erythro-3-hydroxy-Ls-aspartate ammonia-lyase

Systematic name: erythro-3-hydroxy-L-aspartate ammonia-lyase (oxaloacetate-forming)

Comments: A pyridoxal-phosphate protein. The enzyme, which was characterized from the bacterium Paracoccus denitrificans NCIMB 8944, is highly specific for the L-isomer of erythro-3-hydroxyaspartate. Different from EC, threo-3-hydroxy-L-aspartate ammonia-lyase and EC, threo-3-hydroxy-D-aspartate ammonia-lyase. Requires a divalent cation such as Mn2+, Mg2+, and Ca2+.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37290-74-7


1. Gibbs, R.G. and Morris, J.G. Purification and properties of erythro-β-hydroxyaspartate dehydratase from Micrococcus denitrificans. Biochem. J. 97 (1965) 547-554. [PMID: 16749162]

[EC created 1972 as EC, transferred 2001 to EC, modified 2011]

Return to EC 4.3.1 home page
Return to EC 4.3 home page
Return to EC 4 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page