IUBMB Enzyme Nomenclature


Accepted name: deacetylisoipecoside synthase

Reaction: deacetylisoipecoside + H2O = dopamine + secologanin

For diagram click here.

Glossary: dopamine = 4-(2-aminoethyl)benzene-1,2-diol

Other name(s): deacetylisoipecoside dopamine-lyase

Systematic name: deacetylisoipecoside dopamine-lyase (secologanin-forming)

Comments: The enzyme from the leaves of Alangium lamarckii differs in enantiomeric specificity from EC deacetylipecoside synthase. The product is rapidly converted to demethylisoalangiside.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 192827-94-4


1. DeEknamkul, W., Ounaroon, A., Tanahashi, T., Kutchan, T. and Zenk, M.H. Enzymatic condensation of dopamine and secologanin by cell-free extracts of Alangium lamarckii. Phytochemistry 45 (1997) 477-484.

[EC created 2000]

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