IUBMB Enzyme Nomenclature


Accepted name: isoleucine 2-epimerase

Reaction: L-isoleucine = D-allo-isoleucine

Other name(s): BCAA racemase

Systematic name: isoleucine 2-epimerase

Comments: A pyridoxal phosphate protein. The enzyme, characterized from the bacterium Lactobacillus buchneri, specifically catalyses racemization of nonpolar amino acids at the C-2 position.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number:


1. Mutaguchi, Y., Ohmori, T., Wakamatsu, T., Doi, K. and Ohshima, T. Identification, purification, and characterization of a novel amino acid racemase, isoleucine 2-epimerase, from Lactobacillus species. J. Bacteriol. 195 (2013) 5207-5215. [PMID: 24039265]

[EC created 2015]

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