IUBMB Enzyme Nomenclature


Accepted name: isocitrate epimerase

Reaction: (1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate = (1S,2S)-1-hydroxypropane-1,2,3-tricarboxylate

For diagram click here.

Glossary: isocitrate = (1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate = threo-Ds-isocitrate
allocitrate = (1S,2S)-1-hydroxypropane-1,2,3-tricarboxylate = D-erythro-isocitrate

Systematic name: (1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate 1-epimerase

Comments: (1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate is the commonly occurring isomer of isocitrate.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 81210-68-6


1. Hoshiko, S., Kunimoto, Y., Arima, K. and Beppu, T. Mechanism of L-alloisocitric acid fermentation: isocitrate epimerase activity in the cell-free-extract of Penicillium purpurogenum. Agric. Biol. Chem. 46 (1982) 143-151.

[EC created 1984]

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