IUBMB Enzyme Nomenclature


Accepted name: UDP-glucose 4-epimerase

Reaction: UDP-glucose = UDP-galactose

For diagram of reaction click here.

Other name(s): UDP-galactose 4-epimerase; uridine diphosphoglucose epimerase; galactowaldenase; UDPG-4-epimerase; uridine diphosphate galactose 4-epimerase; uridine diphospho-galactose-4-epimerase; UDP-glucose epimerase; UDP-galactose 4-epimerase; 4-epimerase; UDPG-4-epimerase; uridine diphosphoglucose 4-epimerase; uridine diphosphate glucose 4-epimerase; UDP-D-galactose 4-epimerase

Systematic name: UDP-glucose 4-epimerase

Comments: Requires NAD+. Also acts on UDP-2-deoxyglucose.

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9032-89-7


1. Leloir, L.F. Enzymic isomerization and related processes. Adv. Enzymol. Relat. Subj. Biochem. 14 (1953) 193-218.

2. Maxwell, E.S. and de Robichon-Szulmajster, H. Purification of uridine diphosphate galactose-4-epimerase from yeast and the identification of protein-bound diphosphopyridine nucleotide. J. Biol. Chem. 235 (1960) 308-312.

3. Wilson, D.B. and Hogness, D.S. The enzymes of the galactose operon in Escherichia coli. I. Purification and characterization of uridine diphosphogalactose 4-epimerase. J. Biol. Chem. 239 (1964) 2469-2481.

[EC created 1961]

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