Reaction: S-methyl-5-thio-α-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate
For diagram click here.
Other name(s): methylthioribose 1-phosphate isomerase; 1-PMTR isomerase; 5-methylthio-5-deoxy-D-ribose-1-phosphate ketol-isomerase; S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate ketol-isomerase; S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate aldose-ketose-isomerase; 1-phospho-5'-S-methylthioribose isomerase; S-methyl-5-thio-D-ribose-1-phosphate aldose-ketose-isomerase; S-methyl-5-thio-D-ribose-1-phosphate aldose-ketose-isomerase
Systematic name: S-methyl-5-thio-α-D-ribose-1-phosphate aldose-ketose-isomerase
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 91608-95-6
References:
1. Ghoda, L.Y., Savarese, T.M., Dexter, D.L., Parks, R.E., Jr., Trackman, P.C. and Abeles, R.H. Characterization of a defect in the pathway for converting 5'-deoxy-5'-methylthioadenosine to methionine in a subline of a cultured heterogeneous human colon carcinoma. J. Biol. Chem. 259 (1984) 6715-6719. [PMID: 6725268]
2. Trackman, P.C. and Abeles, R.H. Methionine synthesis from 5'-S-methylthioadenosine - resolution of enzyme-activities and identification of 1-phospho-5-S-methylthioribulose. J. Biol. Chem. 258 (1983) 6717-6720. [PMID: 6853500]
3. Furfine, E.S. and Abeles, R.H. Intermediates in the conversion of 5′-S-methylthioadenosine to methionine in Klebsiella pneumoniae. J. Biol. Chem. 263 (1988) 9598-9606. [PMID: 2838472]