IUBMB Enzyme Nomenclature


Accepted name: D-erythrulose-4-phosphate isomerase

Reaction: D-erythrulose 4-phosphate = D-erythrose 4-phosphate

Other name(s): eryI (gene name)

Systematic name: D-erythrulose-4-phosphate ketose-aldose isomerase

Comments: The enzyme, characterized from the pathogenic bacterium Brucella abortus, which causes brucellosis in livestock, participates in erythritol catabolism.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Barbier, T., Collard, F., Zuniga-Ripa, A., Moriyon, I., Godard, T., Becker, J., Wittmann, C., Van Schaftingen, E. and Letesson, J.J. Erythritol feeds the pentose phosphate pathway via three new isomerases leading to D-erythrose-4-phosphate in Brucella. Proc. Natl. Acad. Sci. USA 111 (2014) 17815-17820. [PMID: 25453104]

[EC created 2016]

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