IUBMB Enzyme Nomenclature


Accepted name: aconitate Δ-isomerase

Reaction: trans-aconitate = cis-aconitate

Glossary: cis-aconitate = (Z)-prop-1-ene-1,2,3-tricarboxylate
trans-aconitate = (E)-prop-1-ene-1,2,3-tricarboxylate

Other name(s): aconitate isomerase

Systematic name: aconitate Δ23-isomerase

Comments: cis-Aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3-tricarboxylate. This isomerization could take place either in a direct cis-trans interconversion or by an allylic rearrangement; the enzyme has been shown to catalyse the latter change.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37318-48-2


1. Klinman, J.P. and Rose, I.A. Purification and kinetic properties of aconitate isomerase from Pseudomonas putida. Biochemistry 10 (1971) 2253-2259.

2. Klinman, J.P. and Rose, I.A. Mechanism of the aconitate isomerase reaction. Biochemistry 10 (1971) 2259-2266.

[EC created 1972]

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