IUBMB Enzyme Nomenclature


Accepted name: glutamate 2,3-aminomutase

Reaction: L-glutamate = 3-aminopentanedioate

Glossary: 3-aminopentanedioate = isoglutamate

Systematic name: L-glutamate 2,3-aminomutase

Comments: This enzyme is a member of the 'AdoMet radical' (radical SAM) family. It contains pyridoxal phosphate and a [4Fe-4S] cluster, which is coordinated by 3 cysteines and binds an exchangeable S-adenosyl-L-methionine molecule. During the reaction cycle, the AdoMet forms a 5'-deoxyadenosyl radical, which is regenerated at the end of the reaction.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Ruzicka, F.J. and Frey, P.A. Glutamate 2,3-aminomutase: a new member of the radical SAM superfamily of enzymes. Biochim. Biophys. Acta 1774 (2007) 286-296. [PMID: 17222594]

[EC created 2012]

Return to EC 5.4.3 home page
Return to EC 5.4 home page
Return to EC 5 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page