IUBMB Enzyme Nomenclature


Accepted name: germanicol synthase

Reaction: (3S)-2,3-epoxy-2,3-dihydrosqualene = germanicol

For diagram of reaction click here.

Other name(s): RsM1; (S)-2,3-epoxysqualene mutase (cyclizing, germanicol-forming)

Systematic name: (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, germanicol-forming)

Comments: The enzyme produces germanicol, β-amyrin and lupeol in the ratio 63:33:4.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Basyuni, M., Oku, H., Tsujimoto, E., Kinjo, K., Baba, S. and Takara, K. Triterpene synthases from the Okinawan mangrove tribe, Rhizophoraceae. FEBS J. 274 (2007) 5028-5042. [PMID: 17803686]

[EC created 2011]

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