IUBMB Enzyme Nomenclature


Accepted name: camelliol C synthase

Reaction: (3S)-2,3-epoxy-2,3-dihydrosqualene = camelliol C

For diagram of reaction click here.

Other name(s): CAMS1; LUP3 (gene name)

Systematic name: (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, camelliol-C-forming)

Comments: The product is 97% camelliol, 2% achilleol A and 0.2% β-amyrin. Achilleol is an isomer of camelliol C with a 4-methylenecyclohexanol ring system. This enzyme probably evolved from EC, β-amyrin synthase.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Kolesnikova, M.D., Wilson, W.K., Lynch, D.A., Obermeyer, A.C. and Matsuda, S.P. Arabidopsis camelliol C synthase evolved from enzymes that make pentacycles. Org. Lett. 9 (2007) 5223-5226. [PMID: 17985917]

[EC created 2011]

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