IUBMB Enzyme Nomenclature

EC 5.4.99.40

Accepted name: α-amyrin synthase

Reaction: (3S)-2,3-epoxy-2,3-dihydrosqualene = α-amyrin

For diagram of reaction click here.

Other name(s): 2,3-oxidosqualene α-amyrin cyclase; mixed amyrin synthase

Systematic name: (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, α-amyrin-forming)

Comments: A multifunctional enzyme which produces both α- and β-amyrin. (see EC 5.4.99.39, β-amyrin synthase)

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:

References:

1. Morita, M., Shibuya, M., Kushiro, T., Masuda, K. and Ebizuka, Y. Molecular cloning and functional expression of triterpene synthases from pea (Pisum sativum) new α-amyrin-producing enzyme is a multifunctional triterpene synthase. Eur. J. Biochem. 267 (2000) 3453-3460. [PMID: 10848960]

[EC 5.4.99.40 created 2011]


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