IUBMB Enzyme Nomenclature


Accepted name: marneral synthase

Reaction: (3S)-2,3-epoxy-2,3-dihydrosqualene = marneral

Systematic name: (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, marneral-forming)

For diagram of reaction click here.

Comments: Marneral is a triterpenoid formed by Grob fragmentation of the A ring of 2,3-epoxy-2,3-dihydrosqualene during cyclization.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Xiong, Q., Wilson, W. K. and Matsuda, S. P. T. An Arabidopsis oxidosqualene cyclase catalyzes iridal skeleton formation by Grob fragmentation. Angew. Chem., Int. Ed. 45 (2006) 1285-1288. [PMID: 16425307]

[EC created 2011]

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