IUBMB Enzyme Nomenclature


Accepted name: baruol synthase

Reaction: (3S)-2,3-epoxy-2,3-dihydrosqualene = baruol

For diagram of reaction click here.

Other name(s): BARS1

Systematic name: (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, baruol-forming)

Comments: The enzyme from Arabidopsis thaliana also produces traces of 22 other triterpenoids.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Lodeiro, S., Xiong, Q., Wilson, W.K., Kolesnikova, M.D., Onak, C.S. and Matsuda, S.P. An oxidosqualene cyclase makes numerous products by diverse mechanisms: a challenge to prevailing concepts of triterpene biosynthesis. J. Am. Chem. Soc. 129 (2007) 11213-11222. [PMID: 17705488]

[EC created 2012]

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