IUBMB Enzyme Nomenclature


Accepted name: (+)-kolavenyl diphosphate synthase

Reaction: geranylgeranyl diphosphate = (+)-kolavenyl diphosphate

For diagram of reaction click here

Glossary: (+) kolavenyl diphosphate = (2E)-3-methyl-5-[(1R,2S,4aS,8aS)-1,2,4a,5-tetramethyl-1,2,3,4,4a,7,8,8a-octahydronaphthalen-1-yl]pent-2-en-1-yl diphosphate

Systematic name: (+)-kolavenyl-diphosphate lyase (ring-opening)

Comments: Isolated from the bacterium Herpetosiphon aurantiacus.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Nakano, C., Oshima, M., Kurashima, N. and Hoshino, T. Identification of a new diterpene biosynthetic gene cluster that produces O-methylkolavelool in Herpetosiphon aurantiacus. Chembiochem 16 (2015) 772-781. [PMID: 25694050]

[EC created 2017]

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