IUBMB Enzyme Nomenclature

EC 6.2.1.17

Accepted name: propionate—CoA ligase

Reaction: ATP + propanoate + CoA = AMP + diphosphate + propanoyl-CoA

Other name(s): propionyl-CoA synthetase

Systematic name: propanoate:CoA ligase (AMP-forming)

Comments: Propenoate can act instead of propanoate. Not identical with EC 6.2.1.1 (acetate—CoA ligase) or EC 6.2.1.2 (butyrate—CoA ligase).

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 55326-49-3

References:

1. Ricks, C.A. and Cook, R.M. Regulation of volatile fatty acid uptake by mitochondrial acyl CoA synthetases of bovine liver. J. Dairy Sci. 64 (1981) 2324-2335. [PMID: 7341659]

[EC 6.2.1.17 created 1984]


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