IUBMB Enzyme Nomenclature


Accepted name: propionate—CoA ligase

Reaction: ATP + propanoate + CoA = AMP + diphosphate + propanoyl-CoA

Other name(s): propionyl-CoA synthetase

Systematic name: propanoate:CoA ligase (AMP-forming)

Comments: Propenoate can act instead of propanoate. Not identical with EC (acetate—CoA ligase) or EC (butyrate—CoA ligase).

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 55326-49-3


1. Ricks, C.A. and Cook, R.M. Regulation of volatile fatty acid uptake by mitochondrial acyl CoA synthetases of bovine liver. J. Dairy Sci. 64 (1981) 2324-2335. [PMID: 7341659]

[EC created 1984]

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