IUBMB Enzyme Nomenclature


Accepted name: 4-methyleneglutamate—ammonia ligase

Reaction: ATP + 4-methylene-L-glutamate + NH3 = AMP + diphosphate + 4-methylene-L-glutamine

Other name(s): 4-methyleneglutamine synthetase

Systematic name: 4-methylene-L-glutamate:ammonia ligase (AMP-forming)

Comments: Glutamine can act instead of NH3, but more slowly.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 85537-85-5


1. Winter, H.C., Su, T.-Z. and Dekker, E.E. 4-Methyleneglutamine synthetase: a new amide synthetase present in germinating peanuts. Biochem. Biophys. Res. Commun. 111 (1983) 484-489. [PMID: 6838571]

[EC created 1986]

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