IUBMB Enzyme Nomenclature


Accepted name: γ-glutamylhistamine synthase

Reaction: ATP + L-glutamate + histamine = products of ATP breakdown + Nα-γ-L-glutamylhistamine

Other name(s): γ-glutaminylhistamine synthetase; γ-GHA synthetase

Systematic name: L-glutamate:histamine ligase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 82904-08-3


1. Stein, C. and Weinreich, D. An in vitro characterization of γ-glutamylhistamine synthetase: a novel enzyme catalyzing histamine metabolism in the central nervous system of the marine mollusk, Aplysia californica. J. Neurochem. 38 (1982) 204-214. [PMID: 6125565]

[EC created 1986]

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