Reaction: ATP + 5-phospho-D-ribosylamine + glycine = ADP + phosphate + N1-(5-phospho-D-ribosyl)glycinamide
For reaction pathway click here.
Other name(s): phosphoribosylglycinamide synthetase; glycinamide ribonucleotide synthetase; phosphoribosylglycineamide synthetase; glycineamide ribonucleotide synthetase; 2-amino-N-ribosylacetamide 5'-phosphate kinosynthase; 5'-phosphoribosylglycinamide synthetase; GAR
Systematic name: 5-phospho-D-ribosylamine:glycine ligase (ADP-forming)
Comments: Formerly EC 6.3.1.3.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9032-01-3
References:
1. Goldthwait, D.A., Peabody, R.A. and Greenberg, G.R. On the mechanism of synthesis of glycinamide ribotide and its formyl derivative. J. Biol. Chem. 221 (1956) 569-577.
2. Hartman, S.C. and Buchanan, J.M. Biosynthesis of the purines. XXII. 2-Amino-N-ribosylacetamide-5'-phosphate kinosynthase. J. Biol. Chem. 233 (1958) 456-461.