IUBMB Enzyme Nomenclature


Accepted name: ribose-5-phosphate—ammonia ligase

Reaction: ATP + ribose 5-phosphate + NH3 = ADP + phosphate + 5-phosphoribosylamine

For diagram of reaction click here.

Other name(s): 5-phosphoribosylamine synthetase; ribose 5-phosphate aminotransferase; ammonia-ribose 5-phosphate aminotransferase

Systematic name: ribose-5-phosphate:ammonia ligase (ADP-forming)

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9082-52-4


1. Reem, G.H. Enzymatic synthesis of 5'-phosphoribosylamine from ribose 5-phosphate and ammonia, an alternate first step in purine biosynthesis. J. Biol. Chem. 243 (1968) 5695-5701. [PMID: 5699059]

[EC created 1972]

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