IUBMB Enzyme Nomenclature


Accepted name: biotin—[methylmalonyl-CoA-carboxytransferase] ligase

Reaction: ATP + biotin + apo-[methylmalonyl-CoA:pyruvate carboxytransferase] = AMP + diphosphate + [methylmalonyl-CoA:pyruvate carboxytransferase]

Other name(s): biotin-[methylmalonyl-CoA-carboxyltransferase] synthetase; biotin-methylmalonyl coenzyme A carboxyltransferase synthetase; biotin-transcarboxylase synthetase; methylmalonyl coenzyme A holotranscarboxylase synthetase; biotin—[methylmalonyl-CoA-carboxyltransferase] ligase; biotin:apo[methylmalonyl-CoA:pyruvate carboxyltransferase] ligase (AMP-forming)

Systematic name: biotin:apo[methylmalonyl-CoA:pyruvate carboxytransferase] ligase (AMP-forming)

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37318-66-4


1. Lane, M.D., Young, D.L. and Lynen, F. The enzymatic synthesis of holotranscarboxylase from apotranscarboxylase and (+)-biotin. I. Purification of the apoenzyme and synthetase; characteristics of the reaction. J. Biol. Chem. 239 (1964) 2858-2864.

[EC created 1972]

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