Reaction: ATP + H2O + Zn2+-[zinc-binding protein][side 1] = ADP + phosphate + Zn2+[side 2] + [zinc-binding protein][side 1]
Other name(s): Zn2+-transporting ATPase; Zn2+ ABC transporter; znuABC (gene names)
Systematic name: ATP phosphohydrolase (ABC-type, Zn2+-importing)
Comments: ABC-type (ATP-binding cassette-type) transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. A bacterial enzyme that interacts with an extracytoplasmic substrate binding protein and mediates the high-affinity import of Zn2+.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:
References:
1. Patzer, S.I. and Hantke, K. The ZnuABC high-affinity zinc uptake system and its regulator Zur in Escherichia coli. Mol. Microbiol. 28 (1998) 1199-1210. [PMID: 9680209]
2. Hantke, K. Bacterial zinc uptake and regulators. Curr Opin Microbiol 8 (2005) 196-202. [PMID: 15802252]