IUBMB Enzyme Nomenclature


Accepted name: P-type K+ transporter

Reaction: ATP + H2O + K+[side 1] = ADP + phosphate + K+[side 2]

Other name(s): K+-translocating Kdp-ATPase; multi-subunit K+-transport ATPase; K+-transporting ATPase; potassium-importing ATPase; K+-importing ATPase

Systematic name: ATP phosphohydrolase (P-type, K+-importing)

Comments: A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. A bacterial enzyme that is involved in K+ import. The probable stoichiometry is one ion per ATP hydrolysed.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Siebers, A. and Altendorf, K. Characterization of the phosphorylated intermediate of the K+-translocating Kdp-ATPase from Escherichia coli. J. Biol. Chem. 264 (1989) 5831-5838. [PMID: 2522440]

2. Gassel, M., Siebers, A., Epstein, W. and Altendorf, K. Assembly of the Kdp complex, the multi-subunit K+-transport ATPase of Escherichia coli. Biochim. Biophys. Acta 1415 (1998) 77-84. [PMID: 9858692]

3. Huang, C.S., Pedersen, B.P. and Stokes, D.L. Crystal structure of the potassium-importing KdpFABC membrane complex. Nature 546 (2017) 681-685. [PMID: 28636601]

[EC created 2000 as EC, transferred 2018 to EC]

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