IUBMB Enzyme Nomenclature


Accepted name: ABC-type D-galactose transporter

Reaction: ATP + H2O + D-galactose-[galactose-binding protein][side 1] = ADP + phosphate + D-galactose[side 2] + [galactose-binding protein][side 1]

Other name(s): D-galactose transporting ATPase; D-galactose ABC transporter; mglBAC (gene names)

Systematic name: ATP phosphohydrolase (ABC-type, D-galactose-importing)

Comments: ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. A bacterial enzyme, best characterized from Escherichia coli where it interacts with a periplasmic substrate binding protein and mediates the high affinity uptake of D-galactose and methyl-β-D-galactoside.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Hogg, R.W., Voelker, C. and Von Carlowitz, I. Nucleotide sequence and analysis of the mgl operon of Escherichia coli K12. Mol. Gen. Genet. 229 (1991) 453-459. [PMID: 1719366]

[EC created 2019]

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