IUBMB Enzyme Nomenclature

EC 7.5.2.12

Accepted name: ABC-type L-arabinose transporter

Reaction: ATP + H2O + L-arabinose-[arabinose-binding protein][side 1] = ADP + phosphate + L-arabinose[side 2] + [arabinose-binding protein][side 1]

Other name(s): L-arabinose transporting ATPase; L-arabinose ABC transporter; araFGH (gene names)

Systematic name: ATP phosphohydrolase (ABC-type, L-arabinose-importing)

Comments: ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. A bacterial enzyme that interacts with an extracytoplasmic substrate binding protein and mediates the high-affinity uptake of L-arabinose.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:

References:

1. Scripture, J.B., Voelker, C., Miller, S., O'Donnell, R.T., Polgar, L., Rade, J., Horazdovsky, B.F. and Hogg, R.W. High-affinity L-arabinose transport operon. Nucleotide sequence and analysis of gene products. J. Mol. Biol. 197 (1987) 37-46. [PMID: 2445996]

2. Horazdovsky, B.F. and Hogg, R.W. Genetic reconstitution of the high-affinity L-arabinose transport system. J. Bacteriol. 171 (1989) 3053-3059. [PMID: 2656640]

[EC 7.5.2.12 created 2019]


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