Reaction: ATP + H2O + D-galactofuranose-[galactofuranose-binding protein][side 1] = ADP + phosphate + D-galactofuranose[side 2] + [galactofuranose-binding protein][side 1]
Other name(s): D-galactofuranose transporting ATPase; D-galactofuranose ABC transporter
Systematic name: ATP phosphohydrolase (ABC-type, D-galactofuranose-transporting)
Comments: ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. The enzyme from Escherichai coli interacts with a periplasmic substrate binding protein and mediates the high affinity uptake of D-galactofuranose. The periplasmic binding protein exhibits selective binding of D-galactofuranose over D-galactopyranose.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:
1. Horler, R.S., Muller, A., Williamson, D.C., Potts, J.R., Wilson, K.S. and Thomas, G.H. Furanose-specific sugar transport: characterization of a bacterial galactofuranose-binding protein. J. Biol. Chem 284 (2009) 31156-31163. [PMID: 19744923]