© IUBMB 2001
The mechanism below rationalizes the reaction mechanism, see:
1. Lewis, J., Johnson, K.A. and Anderson, K.S. The catalytic mechanism of EPSP synthase revisited. Biochemistry 38 (1999) 7372-7379. [ PMID: 10353849]
2. Jakeman, D.L., Mitchell, D.J., Shuttleworth, W.A. and Evans, J.N. On the mechanism of 5-enolpyruvylshikimate-3-phosphate synthase. Biochemistry 37 (1998) 12012-12019. [PMID: 9724511]
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© IUBMB 2001
enzymes homepage.
shikimate biosynthesis
EC 2.5.1.19 3-phosphoshikimate 1-carboxyvinyltransferase