New enzymes (17 February 2014, approved 17 February 2014)The entries were added on the date indicated and fully approved after a month. An asterisk before 'EC' indicates that this is an amendment to an existing enzyme rather than a new enzyme entry.
New enzymes (24 June 2014, approved 22 July 2014)
New enzymes (14 October 2014, approved 10 November 2014)
New enzymes (23 December 2014, approved 20 January 2015)
*EC 1.1.1.203 uronate dehydrogenase (23 December 2014)
EC 1.1.1.367 UDP-2-acetamido-2,6-β-L-arabino-hexul-4-ose reductase (17 February 2014)
EC 1.1.1.368 6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase (17 February 2014)
EC 1.1.1.369 D-chiro-inositol 1-dehydrogenase (17 February 2014)
EC 1.1.1.370 scyllo-inositol 2-dehydrogenase (NAD+) (17 February 2014)
EC 1.1.1.371 scyllo-inositol 2-dehydrogenase (NADP+) (17 February 2014)
EC 1.1.1.372 D/L-glyceraldehyde reductase (24 June 2014)
EC 1.1.1.373 sulfolactaldehyde 3-reductase (24 June 2014)
EC 1.1.1.374 UDP-N-acetylglucosamine 3-dehydrogenase (14 October 2014)
EC 1.1.1.375 L-2-hydroxycarboxylate dehydrogenase [NAD(P)+] (14 October 2014)
EC 1.1.1.376 L-arabinose 1-dehydrogenase [NAD(P)+] (14 October 2014)
EC 1.1.1.377 L-rhamnose 1-dehydrogenase (NADP+) (14 October 2014)
EC 1.1.1.378 L-rhamnose 1-dehydrogenase [NAD(P)+] (14 October 2014)
EC 1.1.1.379 (R)-mandelate dehydrogenase (23 December 2014)
EC 1.1.1.380 L-gulonate 5-dehydrogenase (23 December 2014)
EC 1.1.1.381 3-hydroxy acid dehydrogenase (23 December 2014)
EC 1.1.3.3 deleted now EC 1.1.5.4 (24 June 2014)
*EC 1.1.3.19 4-hydroxymandelate oxidase (decarboxylating) (24 June 2014)
EC 1.1.3.46 4-hydroxymandelate oxidase (24 June 2014)
EC 1.1.3.47 5-(hydroxymethyl)furfural oxidase (23 December 2014)
EC 1.1.4.1 transferred, now EC 1.17.4.4 (23 December 2014)
EC 1.1.4.2 transferred, now EC 1.17.4.5 (23 December 2014)
EC 1.1.5.10 D-2-hydroxyacid dehydrogenase (quinone) (17 February 2014)
*EC 1.1.98.3 decaprenylphospho-β-D-ribofuranose 2-dehydrogenase (14 October 2014)
*EC 1.2.1.27 methylmalonate-semialdehyde dehydrogenase (CoA-acylating) (24 June 2014)
EC 1.2.1.89 D-glyceraldehyde dehydrogenase (NADP+) (17 February 2014)
EC 1.2.1.90 glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] (23 December 2014)
EC 1.2.1.91 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase (23 December 2014)
EC 1.2.1.92 3,6-anhydro-α-L-galactose dehydrogenase (23 December 2014)
EC 1.2.99.9 formate dehydrogenase (coenzyme F420) (14 October 2014)
*EC 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific) (24 June 2014)
*EC 1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase (14 October 2014)
*EC 1.3.1.74 2-alkenal reductase [NAD(P)+] (17 February 2014)
EC 1.3.1.106 cobalt-precorrin-6A reductase (17 February 2014)
EC 1.3.1.107 sanguinarine reductase (14 October 2014)
EC 1.3.4 With a disulfide as acceptor (14 October 2014)
EC 1.3.4.1 fumarate reductase (CoM/CoB) (14 October 2014)
*EC 1.3.5.1 succinate dehydrogenase (quinone) (17 February 2014)
*EC 1.3.7.5 phycocyanobilin:ferredoxin oxidoreductase (14 October 2014)
EC 1.3.98.2 fumarate reductase (CoM/CoB) (17 February 2014)
EC 1.3.98.2 transferred now EC 1.3.4.1 (14 October 2014)
EC 1.3.99.1 deleted, included with EC 1.3.5.1 (17 February 2014)
EC 1.3.99.35 chlorophyllide a reductase (17 February 2014)
EC 1.3.99.36 cypemycin cysteine dehydrogenase (decarboxylating) (24 June 2014)
*EC 1.5.1.47 dihydromethanopterin reductase [NAD(P)+] (14 October 2014)
EC 1.5.1.48 2-methyl-1-pyrroline reductase (24 June 2014)
*EC 1.5.4.1 pyrimidodiazepine synthase (24 June 2014)
EC 1.5.98.1 methylenetetrahydromethanopterin dehydrogenase (17 February 2014)
EC 1.5.98.2 5,10-methylenetetrahydromethanopterin reductase (17 February 2014)
EC 1.5.99.9 transferred now EC 1.5.98.1 (17 February 2014)
EC 1.5.99.11 transferred now EC 1.5.98.2 (17 February 2014)
EC 1.5.99.15 dihydromethanopterin reductase (acceptor) (14 October 2014)
EC 1.6.3.5 renalase (17 February 2014)
EC 1.8.98.3 sulfite reductase (coenzyme F420) (14 October 2014)
EC 1.9.98 With other, known, acceptors (23 December 2014)
EC 1.9.98.1 iron—cytochrome-c reductase (23 December 2014)
EC 1.9.99.1 transferred, now EC 1.9.98.1 (23 December 2014)
*EC 1.10.3.10 ubiquinol oxidase (H+-transporting) (24 June 2014)
*EC 1.10.3.11 ubiquinol oxidase (non-electrogenic) (17 February 2014)
EC 1.10.3.15 grixazone synthase (24 June 2014)
EC 1.10.3.14 ubiquinol oxidase (electrogenic, non H+-transporting) (17 February 2014)
EC 1.11.1.23 (S)-2-hydroxypropylphosphonic acid epoxidase (24 June 2014)
EC 1.11.2.5 3-methyl-L-tyrosine peroxygenase (24 June 2014)
EC 1.13.11.78 2-amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming) (24 June 2014)
EC 1.13.11.79 5,6-dimethylbenzimidazole synthase (24 June 2014)
EC 1.14.11.45 L-isoleucine 4-hydroxylase (24 June 2014)
EC 1.14.11.46 2-aminoethylphosphonate dioxygenase (24 June 2014)
EC 1.14.11.47 50S ribosomal protein L16 3-hydroxylase (14 October 2014)
EC 1.14.13.185 pikromycin synthase (17 February 2014)
EC 1.14.13.186 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase (17 February 2014)
EC 1.14.13.187 L-evernosamine nitrososynthase (17 February 2014)
EC 1.14.13.188 6-deoxyerythronolide B hydroxylase (17 February 2014)
EC 1.14.13.189 5-methyl-1-naphthoate 3-hydroxylase (24 June 2014)
EC 1.14.13.190 ferruginol synthase (24 June 2014)
EC 1.14.13.191 ent-sandaracopimaradiene 3-hydroxylase (24 June 2014)
EC 1.14.13.192 oryzalexin E synthase (24 June 2014)
EC 1.14.13.193 oryzalexin D synthase (24 June 2014)
EC 1.14.13.194 phylloquinone ω-hydroxylase (24 June 2014)
EC 1.14.13.195 L-ornithine N5-monooxygenase (NADPH) (14 October 2014)
EC 1.14.13.196 L-ornithine N5-monooxygenase [NAD(P)H] (14 October 2014)
EC 1.14.13.197 dihydromonacolin L hydroxylase (14 October 2014)
EC 1.14.13.198 monacolin L hydroxylase (14 October 2014)
EC 1.14.13.199 docosahexaenoic acid ω-hydroxylase (14 October 2014)
EC 1.14.13.200 tetracenomycin A2 monooxygenase-dioxygenase (14 October 2014)
EC 1.14.14.7 transferred now EC 1.14.19.9 (14 October 2014)
EC 1.14.14.15 (3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[peptidyl-carrier protein SgcC2] monooxygenase (24 June 2014)
*EC 1.14.15.4 steroid 11β-monooxygenase (14 October 2014)
*EC 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving) (14 October 2014)
EC 1.14.16.7 phenylalanine 3-monooxygenase (24 June 2014)
EC 1.14.19.7 transferred now EC 1.11.1.23 (24 June 2014)
EC 1.14.19.9 tryptophan 7-halogenase (14 October 2014)
EC 1.14.99.40 transferred now EC 1.13.11.79 (24 June 2014)
*EC 1.14.99.42 zeaxanthin 7,8-dioxygenase (23 December 2014)
EC 1.14.99.49 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase (14 October 2014)
EC 1.16.3.2 bacterial non-heme ferritin (24 June 2014)
*EC 1.16.1.7 ferric-chelate reductase (NADH) (17 February 2014)
*EC 1.16.1.9 ferric-chelate reductase (NADPH) (17 February 2014)
EC 1.16.1.10 ferric-chelate reductase [NAD(P)H] (17 February 2014)
EC 1.17.1.7 transferred, now EC 1.2.1.91 (23 December 2014)
EC 1.17.4.4 vitamin-K-epoxide reductase (warfarin-sensitive) (23 December 2014)
EC 1.17.4.5 vitamin-K-epoxide reductase (warfarin-insensitive) (23 December 2014)
*EC 1.17.7.1 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin) (23 December 2014)
EC 1.17.7.3 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin) (23 December 2014)
EC 1.17.98 With other, known, acceptors (23 December 2014)
EC 1.17.98.1 bile-acid 7α-dehydroxylase (23 December 2014)
EC 1.17.99.5 transferred, now EC 1.17.98.1 (23 December 2014)
EC 1.17.99.6 epoxyqueuosine reductase (23 December 2014)
*EC 1.19.6.1 nitrogenase (flavodoxin) (23 December 2014)
EC 1.21.98 With other, known, acceptors (23 December 2014)
EC 1.21.98.1 cyclic dehypoxanthinyl futalosine synthase (23 December 2014)
EC 1.21.99.2 cyclic dehypoxanthinyl futalosine synthase (17 February 2014)
EC 1.21.99.2 transferred, now EC 1.21.98.1 (23 December 2014)
*EC 2.1.1.57 methyltransferase cap1 (28 March 2014)
*EC 2.1.1.192 23S rRNA (adenine2503-C2)-methyltransferase (23 December 2014)
*EC 2.1.1.224 23S rRNA (adenine2503-C8)-methyltransferase (23 December 2014)
*EC 2.1.1.267 flavonoid 3',5'-methyltransferase (17 February 2014)
*EC 2.1.1.282 tRNAPhe 7-[(3-amino-3-carboxypropyl)-4-demethylwyosine37-N4]-methyltransferase (17 February 2014)
EC 2.1.1.294 3-O-phospho-polymannosyl GlcNAc-diphospho-ditrans,octacis-undecaprenol 3-phospho-methyltransferase (17 February 2014)
EC 2.1.1.295 2-methyl-6-phytyl-1,4-hydroquinone methyltransferase (17 February 2014)
EC 2.1.1.296 methyltransferase cap2 (28 March 2014)
EC 2.1.1.297 peptide chain release factor N5-glutamine methyltransferase (17 February 2014)
EC 2.1.1.298 ribosomal protein L3 N5-glutamine methyltransferase (17 February 2014)
EC 2.1.1.299 protein N-terminal monomethyltransferase (17 February 2014)
EC 2.1.1.300 pavine N-methyltransferase (17 February 2014)
EC 2.1.1.301 cypemycin N-terminal methyltransferase (24 June 2014)
EC 2.1.1.302 3-hydroxy-5-methyl-1-naphthoate 3-O-methyltransferase (24 June 2014)
EC 2.1.1.303 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase (24 June 2014)
EC 2.1.1.304 L-tyrosine C3-methyltransferase (24 June 2014)
EC 2.1.1.305 8-demethyl-8-α-L-rhamnosyltetracenomycin-C 2'-O-methyltransferase (24 June 2014)
EC 2.1.1.306 8-demethyl-8-(2-methoxy-α-L-rhamnosyl)tetracenomycin-C 3'-O-methyltransferase (24 June 2014)
EC 2.1.1.307 8-demethyl-8-(2,3-dimethoxy-α-L-rhamnosyl)tetracenomycin-C 4'-O-methyltransferase (24 June 2014)
EC 2.1.1.308 2-hydroxyethylphosphonate methyltransferase (23 December 2014)
EC 2.1.1.309 18S rRNA (guanine1575-N7)-methyltransferase (23 December 2014)
EC 2.1.1.310 25S rRNA (cytosine2870-C5)-methyltransferase (23 December 2014)
EC 2.1.1.311 25S rRNA (cytosine2278-C5)-methyltransferase (23 December 2014)
EC 2.1.1.312 25S rRNA (uracil2843-N3)-methyltransferase (23 December 2014)
EC 2.1.1.313 25S rRNA (uracil2634-N3)-methyltransferase (23 December 2014)
EC 2.1.3.13 deleted now covered by EC 6.1.2.2 (24 June 2014)
EC 2.1.3.14 deleted now covered by EC 6.1.2.2 (24 June 2014)
EC 2.2.1.12 3-acetyloctanal synthase (23 December 2014)
EC 2.3.1.232 methanol O-anthraniloyltransferase (17 February 2014)
EC 2.3.1.233 1,3,6,8-tetrahydroxynaphthalene synthase (24 June 2014)
EC 2.3.1.234 N6-L-threonylcarbamoyladenine synthase (23 December 2014)
EC 2.3.1.235 tetracenomycin F2 synthase (23 December 2014)
EC 2.3.1.236 5-methylnaphthoic acid synthase (23 December 2014)
EC 2.3.1.237 neocarzinostatin naphthoate synthase (23 December 2014)
EC 2.3.1.238 monacolin J acid methylbutanoate transferase (23 December 2014)
EC 2.3.1.239 10-deoxymethynolide synthase (23 December 2014)
EC 2.3.1.240 narbonolide synthase (23 December 2014)
EC 2.3.1.241 Kdo2-lipid IVA lauroyltransferase (23 December 2014)
EC 2.3.1.242 Kdo2-lipid IVA palmitoleoyltransferase (23 December 2014)
EC 2.3.1.243 lauroyl-Kdo2-lipid IVA myristoyltransferase (23 December 2014)
*EC 2.3.3.1 citrate (Si)-synthase (17 February 2014)
EC 2.3.3.16 citrate synthase (unknown stereospecificity) (17 February 2014)
*EC 2.4.1.109 dolichyl-phosphate-mannose—protein mannosyltransferase (14 October 2014)
*EC 2.4.1.277 10-deoxymethynolide desosaminyltransferase (17 February 2014)
*EC 2.4.1.278 3-α-mycarosylerythronolide B desosaminyl transferase (17 February 2014)
EC 2.4.1.315 diglucosyl diacylglycerol synthase (1,6-linking) (17 February 2014)
EC 2.4.1.316 tylactone mycaminosyltransferase (17 February 2014)
EC 2.4.1.317 O-mycaminosyltylonolide 6-deoxyallosyltransferase (17 February 2014)
EC 2.4.1.318 demethyllactenocin mycarosyltransferase (17 February 2014)
EC 2.4.1.319 β-1,4-mannooligosaccharide phosphorylase (17 February 2014)
EC 2.4.1.320 1,4-β-mannosyl-N-acetylglucosamine phosphorylase (17 February 2014)
EC 2.4.1.321 cellobionic acid phosphorylase (17 February 2014)
EC 2.4.1.322 desvancosaminyl-vancomycin vancosaminetransferase (17 February 2014)
EC 2.4.1.323 7-deoxyloganetic acid glucosyltransferase (17 February 2014)
EC 2.4.1.324 7-deoxyloganetin glucosyltransferase (17 February 2014)
*EC 2.4.1.208 diglucosyl diacylglycerol synthase (1,2-linking) (24 June 2014)
EC 2.4.1.325 TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase (24 June 2014)
EC 2.4.1.326 aklavinone 7-β-L-rhodosaminyltransferase (24 June 2014)
EC 2.4.1.327 aclacinomycin-T 2-deoxy-L-fucose transferase (24 June 2014)
EC 2.4.1.328 erythronolide mycarosyltransferase (24 June 2014)
EC 2.4.1.329 sucrose 6F-phosphate phosphorylase (14 October 2014)
EC 2.4.1.330 β-D-glucosyl crocetin β-1,6-glucosyltransferase (14 October 2014)
EC 2.4.1.331 8-demethyltetracenomycin C L-rhamnosyltransferase (14 October 2014)
EC 2.4.1.332 1,2-α-glucosylglycerol phosphorylase (23 December 2014)
EC 2.4.1.333 1,2-β-oligoglucan phosphorylase (23 December 2014)
EC 2.4.1.334 1,3-α-oligoglucan phosphorylase (23 December 2014)
*EC 2.4.2.35 flavonol-3-O-glycoside xylosyltransferase (17 February 2014)
*EC 2.4.2.54 β-ribofuranosylhydroxybenzene 5'-phosphate synthase (23 December 2014)
EC 2.4.2.57 AMP phosphorylase (17 February 2014)
EC 2.4.99.20 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase (17 February 2014)
*EC 2.5.1.25 tRNA-uridine aminocarboxypropyltransferase (23 December 2014)
EC 2.5.1.115 homogentisate phytyltransferase (17 February 2014)
EC 2.5.1.116 homogentisate geranylgeranyltransferase (17 February 2014)
EC 2.5.1.117 homogentisate solanesyltransferase (17 February 2014)
EC 2.5.1.118 β-(isoxazolin-5-on-2-yl)-L-alanine synthase (17 February 2014)
EC 2.5.1.119 β-(isoxazolin-5-on-4-yl)-L-alanine synthase (17 February 2014)
EC 2.5.1.120 aminodeoxyfutalosine synthase (17 February 2014)
EC 2.5.1.121 5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase (24 June 2014)
EC 2.5.1.122 4-O-dimethylallyl-L-tyrosine synthase (24 June 2014)
EC 2.5.1.123 flaviolin linalyltransferase (24 June 2014)
EC 2.5.1.124 6-linalyl-2-O,3-dimethylflaviolin synthase (14 October 2014)
EC 2.5.1.125 7-geranyloxy-5-hydroxy-2-methoxy-3-methylnaphthalene-1,4-dione synthase (14 October 2014)
EC 2.5.1.126 norspermine synthase (14 October 2014)
EC 2.5.1.127 caldopentamine synthase (14 October 2014)
EC 2.5.1.128 N4-bis(aminopropyl)spermidine synthase (23 December 2014)
EC 2.6.1.104 3-dehydro-glucose-6-phosphate—glutamate transaminase (17 February 2014)
EC 2.6.1.105 lysine—8-amino-7-oxononanoate transaminase (17 February 2014)
EC 2.6.1.106 dTDP-3-amino-3,4,6-trideoxy-α-D-glucose transaminase (17 February 2014)
EC 2.6.1.107 β-methylphenylalanine transaminase (17 February 2014)
EC 2.6.99.4 N6-L-threonylcarbamoyladenine synthase (17 February 2014)
EC 2.6.99.4 transferred, now EC 2.3.1.234 (23 December 2014)
*EC 2.7.1.8 glucosamine kinase (14 October 2014)
EC 2.7.1.181 polymannosyl GlcNAc-diphospho-ditrans,octacis-undecaprenol kinase (17 February 2014)
EC 2.7.1.182 phytol kinase (17 February 2014)
EC 2.7.1.183 glycoprotein-mannosyl O6-kinase (24 June 2014)
EC 2.7.1.184 sulfofructose kinase (24 June 2014)
EC 2.7.1.185 mevalonate 3-kinase (14 October 2014)
EC 2.7.1.186 mevalonate-3-phosphate 5-kinase (14 October 2014)
*EC 2.7.4.24 diphosphoinositol-pentakisphosphate kinase (17 February 2014)
*EC 2.7.7.67 CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase (23 December 2014)
*EC 2.7.7.86 cyclic GMP-AMP synthase (24 June 2014)
EC 2.7.8.41 cardiolipin synthase (CMP-forming) (23 December 2014)
EC 2.7.14 Protein-arginine kinases (14 October 2014)
EC 2.7.14.1 protein arginine kinase (14 October 2014)
*EC 2.8.1.6 biotin synthase (23 December 2014)
*EC 2.8.1.8 lipoyl synthase (23 December 2014)
EC 2.8.2.36 desulfo-A47934 sulfotransferase (17 February 2014)
EC 2.8.2.37 trehalose 2-sulfotransferase (24 June 2014)
EC 2.8.3.7 deleted now EC 2.8.3.20 and EC 2.8.3.22 (17 February 2014)
EC 2.8.3.20 succinyl-CoA—D-citramalate CoA-transferase (17 February 2014)
EC 2.8.3.21 L-carnitine CoA-transferase (17 February 2014)
EC 2.8.3.22 succinyl-CoA—L-malate CoA-transferase (17 February 2014)
EC 2.8.4.3 tRNA-2-methylthio-N6-dimethylallyladenosine synthase (17 February 2014)
EC 2.8.4.4 [ribosomal protein S12] (aspartate89-C3)-methylthiotransferase (17 February 2014)
*EC 2.8.4.4 [ribosomal protein S12] (aspartate89-C3)-methylthiotransferase (14 October 2014)
EC 2.8.4.5 tRNA (N6-L-threonylcarbamoyladenosine37-C2)-methylthiotransferase (17 February 2014)
*EC 2.9.1.2 O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase (14 October 2014)
EC 3.1.1.96 D-aminoacyl-tRNA deacylase (24 June 2014)
EC 3.1.1.97 diphthine methylesterase (23 December 2014)
EC 3.1.2.15 deleted (14 October 2014)
EC 3.1.2.30 (3S)-malyl-CoA thioesterase (17 February 2014)
(17 February 2014)
EC 3.1.3.93 L-galactose 1-phosphate phosphatase (17 February 2014)
EC 3.1.3.94 D-galactose 1-phosphate phosphatase (17 February 2014)
EC 3.1.3.95 phosphatidylinositol-3,5-bisphosphate 3-phosphatase (17 February 2014)
EC 3.1.3.96 pseudouridine 5'-phosphatase (23 December 2014)
EC 3.1.4.57 phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase (24 June 2014)
EC 3.1.12 Exodeoxyribonucleases producing 3'-phosphomonoesters (24 June 2014)
EC 3.1.12.1 5' to 3' exodeoxyribonuclease (nucleoside 3'-phosphate-forming) (24 June 2014)
*EC 3.1.21.2 deoxyribonuclease IV (17 February 2014)
EC 3.1.21.8 T4 deoxyribonuclease II (17 February 2014)
EC 3.1.21.9 T4 deoxyribonuclease IV (17 February 2014)
EC 3.1.27.9 transferred now EC 4.6.1.16 (17 February 2014)
EC 3.2.1.191 ginsenosidase type III (17 February 2014)
EC 3.2.1.192 ginsenoside Rb1 β-glucosidase (17 February 2014)
EC 3.2.1.193 ginsenosidase type I (17 February 2014)
EC 3.2.1.194 ginsenosidase type IV (17 February 2014)
EC 3.2.1.195 20-O-multi-glycoside ginsenosidase (17 February 2014)
*EC 3.2.2.6 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase (17 February 2014)
EC 3.2.2.30 aminodeoxyfutalosine nucleosidase (17 February 2014)
EC 3.5.1.27 deleted, covered by EC 3.5.1.88 (23 December 2014)
*EC 3.5.1.46 6-aminohexanoate-oligomer exohydrolase (24 June 2014)
EC 3.5.1.116 ureidoglycolate amidohydrolase (17 February 2014)
EC 3.5.1.117 6-aminohexanoate-oligomer endohydrolase (24 June 2014)
EC 3.5.2.20 isatin hydrolase (23 December 2014)
EC 3.5.3.19 transferred now EC 3.5.1.116 (17 February 2014)
*EC 3.5.4.17 adenosine-phosphate deaminase (24 June 2014)
*EC 3.5.4.20 pyrithiamine deaminase (23 December 2014)
EC 3.5.4.40 aminodeoxyfutalosine deaminase (17 February 2014)
EC 3.5.4.41 5'-deoxyadenosine deaminase (14 October 2014)
*EC 3.5.99.7 1-aminocyclopropane-1-carboxylate deaminase (24 June 2014)
EC 3.5.99.10 2-iminobutanoate/2-iminopropanoate deaminase (17 February 2014)
EC 3.6.1.67 dihydroneopterin triphosphate diphosphatase (23 December 2014)
EC 3.7.1.21 6-oxocyclohex-1-ene-1-carbonyl-CoA hydratase (17 February 2014)
EC 3.7.1.22 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing) (17 February 2014)
EC 3.9.1.2 protein arginine phosphatase (14 October 2014)
EC 3.13.1.4 3-sulfinopropanoyl-CoA desulfinase (24 June 2014)
EC 4.1.1.97 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase (17 February 2014)
EC 4.1.1.98 4-hydroxy-3-polyprenylbenzoate decarboxylase (24 June 2014)
EC 4.1.1.99 phosphomevalonate decarboxylase (14 October 2014)
*EC 4.1.2.14 2-dehydro-3-deoxy-phosphogluconate aldolase (17 February 2014)
*EC 4.1.2.21 2-dehydro-3-deoxy-6-phosphogalactonate aldolase (17 February 2014)
EC 4.1.2.55 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase (17 February 2014)
EC 4.1.2.56 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate synthase (17 February 2014)
EC 4.1.2.57 sulfofructosephosphate aldolase (24 June 2014)
*EC 4.1.3.24 malyl-CoA lyase (17 February 2014)
*EC 4.1.3.25 (S)-citramalyl-CoA lyase (17 February 2014)
EC 4.1.3.46 (R)-citramalyl-CoA lyase (17 February 2014)
*EC 4.1.99.19 2-iminoacetate synthase (23 December 2014)
EC 4.2.1.89 deleted, due to EC 2.8.3.21 and EC 4.2.1.119 (17 February 2014)
*EC 4.2.1.121 colneleate synthase (14 October 2014)
*EC 4.2.1.134 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase (24 June 2014)
EC 4.2.1.147 5,6,7,8-tetrahydromethanopterin hydro-lyase (17 February 2014)
EC 4.2.1.148 2-methylfumaryl-CoA hydratase (17 February 2014)
EC 4.2.1.149 crotonobetainyl-CoA hydratase (17 February 2014)
EC 4.2.1.150 short-chain-enoyl-CoA hydratase (17 February 2014)
EC 4.2.1.151 chorismate dehydratase (17 February 2014)
EC 4.2.1.152 hydroperoxy icosatetraenoate dehydratase (24 June 2014)
EC 4.2.1.153 3-methylfumaryl-CoA hydratase (24 June 2014)
EC 4.2.1.154 tetracenomycin F2 cyclase (24 June 2014)
EC 4.2.3.145 ophiobolin F synthase (24 June 2014)
EC 4.2.3.146 cyclooctat-9-en-7-ol synthase (24 June 2014)
EC 4.2.3.147 pimaradiene synthase (14 October 2014)
EC 4.2.3.148 cembrene C synthase (23 December 2014)
EC 4.2.3.149 nephthenol synthase (23 December 2014)
EC 4.2.3.150 cembrene A synthase (23 December 2014)
EC 4.2.3.151 pentamethylcyclopentadecatrienol synthase (23 December 2014)
*EC 4.3.1.17 L-serine ammonia-lyase (17 February 2014)
*EC 4.3.1.19 threonine ammonia-lyase (17 February 2014)
EC 4.3.1.30 dTDP-4-amino-4,6-dideoxy-D-glucose ammonia-lyase (17 February 2014)
*EC 4.3.2.3 ureidoglycolate lyase (17 February 2014)
EC 4.4.1.28 L-cysteine desulfidase (23 December 2014)
EC 4.6.1.16 tRNA-intron lyase (17 February 2014)
EC 5.1.3.28 UDP-N-acetyl-L-fucosamine synthase (17 February 2014)
EC 5.1.3.29 L-fucose mutarotase (24 June 2014)
EC 5.1.3.30 D-psicose 3-epimerase (14 October 2014)
EC 5.1.3.31 D-tagatose 3-epimerase (14 October 2014)
EC 5.1.3.32 L-rhamnose mutarotase (14 October 2014)
EC 5.3.1.30 5-deoxy-glucuronate isomerase (17 February 2014)
EC 5.3.1.31 sulfoquinovose isomerase (24 June 2014)
EC 5.3.99.11 2-keto-myo-inositol isomerase (17 February 2014)
EC 5.4.1.2 transferred now EC 5.4.99.61 (17 February 2014)
EC 5.4.1.3 2-methylfumaryl-CoA isomerase (17 February 2014)
*EC 5.4.2.11 phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) (24 June 2014)
EC 5.4.4.7 hydroperoxy icosatetraenoate isomerase (24 June 2014)
EC 5.4.99.60 cobalt-precorrin-8 methylmutase (17 February 2014)
EC 5.4.99.61 precorrin-8X methylmutase (17 February 2014)
EC 5.4.99.62 D-ribose pyranase (14 October 2014)
*EC 5.5.1.23 aklanonic acid methyl ester cyclase (24 June 2014)
EC 5.5.1.25 3,6-anhydro-α-L-galactonate cycloisomerase (23 December 2014)
EC 6.1.1.28 deleted (14 October 2014)
EC 6.1.2.2 nebramycin 5' synthase (24 June 2014)
EC 6.2.1.40 4-hydroxybutyrate—CoA ligase (17 February 2014)
EC 6.2.1.41 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate—CoA ligase (24 June 2014)
EC 6.2.1.42 3-oxocholest-4-en-26-oate—CoA ligase (24 June 2014)
EC 6.2.1.43 2-hydroxy-7-methoxy-5-methyl-1-naphthoate—CoA ligase (24 June 2014)
EC 6.2.1.44 3-(methylthio)propionyl—CoA ligase (14 October 2014)
*EC 6.3.1.9 trypanothione synthase (24 June 2014)
EC 6.3.1.17 β-citrylglutamate synthase (17 February 2014)
EC 6.3.1.18 γ-glutamylanilide synthase (24 June 2014)
*EC 6.3.2.1 pantoate—β-alanine ligase (AMP-forming) (14 October 2014)
EC 6.3.2.41 N-acetylaspartylglutamate synthase (17 February 2014)
EC 6.3.2.42 N-acetylaspartylglutamylglutamate synthase (17 February 2014)
EC 6.3.2.43 [lysine-biosynthesis-protein LysW]—L-2-aminoadipate ligase (14 October 2014)
EC 6.3.2.44 pantoate—β-alanine ligase (ADP-forming) (14 October 2014)
EC 6.3.2.45 UDP-N-acetylmuramate L-alanyl-γ-D-glutamyl-meso-2,6-diaminoheptandioate ligase (23 December 2014)
*EC 6.3.4.14 biotin carboxylase (23 December 2014)
EC 6.3.4.24 tyramine—L-glutamate ligase (23 December 2014)