New enzymes (17 March 2016, approved 12 April 2016)The entries were added on the date indicated and fully approved after a month. An asterisk before 'EC' indicates that this is an amendment to an existing enzyme rather than a new enzyme entry.
New enzymes (10 August 2016, approved 31 August 2016)
New enzymes (28 September 2016, approved 25 October 2016)
New enzymes (4 December 2016, approved 29 December 2016)
*EC 1.1.1.52 3α-hydroxycholanate dehydrogenase (NAD+) (17 March 2016)
*EC 1.1.1.95 phosphoglycerate dehydrogenase (4 December 2016)
*EC 1.1.1.219 dihydroflavonol 4-reductase (10 August 2016)
*EC 1.1.1.290 4-phosphoerythronate dehydrogenase (10 August 2016)
EC 1.1.1.391 3β-hydroxycholanate 3-dehydrogenase (NAD+) (17 March 2016)
EC 1.1.1.392 3α-hydroxycholanate dehydrogenase (NADP+) (17 March 2016)
EC 1.1.1.393 3β-hydroxycholanate 3-dehydrogenase (NADP+) (17 March 2016)
EC 1.1.1.394 aurachin B dehydrogenase (17 March 2016)
EC 1.1.1.395 3α-hydroxy bile acid-CoA-ester 3-dehydrogenase (10 August 2016)
EC 1.1.1.396 bacteriochlorophyllide a dehydrogenase (10 August 2016)
EC 1.1.1.397 β-methylindole-3-pyruvate reductase (10 August 2016)
EC 1.1.1.398 2-glutathionyl-2-methylbut-3-en-1-ol dehydrogenase (10 August 2016)
EC 1.1.1.399 2-oxoglutarate reductase (10 August 2016)
EC 1.1.1.400 2-methyl-1,2-propanediol dehydrogenase (10 August 2016)
EC 1.1.1.401 2-dehydro-3-deoxy-L-rhamnonate dehydrogenase (NAD+) (10 August 2016)
EC 1.1.1.402 D-erythritol 1-phosphate dehydrogenase (10 August 2016)
EC 1.1.1.403 D-threitol dehydrogenase (NAD+) (10 August 2016)
EC 1.1.2.9 1-butanol dehydrogenase (cytochrome c) (10 August 2016)
EC 1.1.3.49 (R)-mandelonitrile oxidase (28 September 2016)
EC 1.1.5.11 1-butanol dehydrogenase (quinone) (10 August 2016)
*EC 1.2.1.50 long-chain acyl-protein thioester reductase (10 August 2016)
EC 1.2.1.98 2-hydroxy-2-methylpropanal dehydrogenase (10 August 2016)
EC 1.2.3.15 (methyl)glyoxal oxidase (10 August 2016)
EC 1.2.5.3 aerobic carbon monoxide dehydrogenase (17 March 2016)
*EC 1.2.7.4 anaerobic carbon-monoxide dehydrogenase (17 March 2016)
EC 1.2.99.2 transferred now EC 1.2.7.4 (17 March 2016)
*EC 1.3.1.75 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH) (10 August 2016)
*EC 1.3.1.77 anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming] (28 September 2016)
EC 1.3.1.80 transferred now EC 1.3.7.12 (17 March 2016)
EC 1.3.1.111 geranylgeranyl-bacteriochlorophyllide a reductase (17 March 2016)
EC 1.3.1.112 anthocyanidin reductase [(2S)-flavan-3-ol-forming] (28 September 2016)
EC 1.3.3.15 coproporphyrinogen III oxidase (coproporphyrin-forming) (10 August 2016)
EC 1.3.7.12 red chlorophyll catabolite reductase (17 March 2016)
EC 1.3.7.13 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (ferredoxin) (10 August 2016)
EC 1.3.7.14 3,8-divinyl chlorophyllide a reductase (10 August 2016)
EC 1.3.7.15 chlorophyllide a reductase (10 August 2016)
EC 1.3.98.3 coproporphyrinogen dehydrogenase (10 August 2016)
EC 1.3.98.4 5a,11a-dehydrotetracycline reductase (4 December 2016)
EC 1.3.99.22 transferred, now EC 1.3.98.3 (10 August 2016)
EC 1.3.99.35 transferred, now EC 1.3.7.15 (10 August 2016)
EC 1.5.3.23 glyphosate oxidoreductase (4 December 2016)
EC 1.7.2.7 hydrazine synthase (10 August 2016)
EC 1.7.2.8 hydrazine dehydrogenase (10 August 2016)
EC 1.7.99.8 transferred, now EC 1.7.2.8 (10 August 2016)
*EC 1.8.2.1 sulfite dehydrogenase (cytochrome) (4 December 2016)
EC 1.8.5.5 thiosulfate reductase (quinone) (4 December 2016)
EC 1.8.5.6 sulfite dehydrogenase (quinone) (4 December 2016)
EC 1.8.99.3 deleted (10 August 2016)
EC 1.10.3.16 dihydrophenazinedicarboxylate synthase (4 December 2016)
*EC 1.11.1.14 lignin peroxidase (17 March 2016)
*EC 1.11.1.16 versatile peroxidase (17 March 2016)
*EC 1.13.11.63 β-carotene 15,15'-dioxygenase (17 March 2016)
*EC 1.14.11.9 flavanone 3-dioxygenase (4 December 2016)
EC 1.14.11.50 (–)-deoxypodophyllotoxin synthase (17 March 2016)
EC 1.14.11.51 DNA N6-methyladenine demethylase (10 August 2016)
EC 1.14.11.52 validamycin A dioxygenase (10 August 2016)
EC 1.14.11.53 mRNA N6-methyladenine demethylase (10 August 2016)
EC 1.14.11.54 mRNA N1-methyladenine demethylase (28 September 2016)
EC 1.14.12.20 transferred now EC 1.14.15.17 (17 March 2016)
EC 1.14.12.25 p-cumate 2,3-dioxygenase (4 December 2016)
*EC 1.14.13.7 phenol 2-monooxygenase (NADPH) (17 March 2016)
EC 1.14.13.13 transferred, now EC 1.14.15.18 (10 August 2016)
EC 1.14.13.15 transferred now EC 1.14.15.15 (17 March 2016)
EC 1.14.13.17 transferred now EC 1.14.14.23 (17 March 2016)
*EC 1.14.13.38 anhydrotetracycline 6-monooxygenase (4 December 2016)
EC 1.14.13.41 now EC 1.14.14.36 (4 December 2016)
EC 1.14.13.68 now EC 1.14.14.37 (4 December 2016)
EC 1.14.13.90 now EC 1.14.15.21 (4 December 2016)
EC 1.14.13.98 transferred now EC 1.14.14.25 (17 March 2016)
EC 1.14.13.99 transferred now EC 1.14.14.26 (17 March 2016)
EC 1.14.13.100 transferred, now EC 1.14.14.29 (10 August 2016)
*EC 1.14.13.111 methanesulfonate monooxygenase (NADH) (4 December 2016)
EC 1.14.13.126 transferred now EC 1.14.15.16 (17 March 2016)
*EC 1.14.13.141 cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming] (10 August 2016)
EC 1.14.13.159 transferred now EC 1.14.14.24 (17 March 2016)
EC 1.14.13.207 transferred now EC 1.14.14.31 (28 September 2016)
EC 1.14.13.210 4-methyl-5-nitrocatechol 5-monooxygenase (17 March 2016)
EC 1.14.13.211 rifampicin monooxygenase (17 March 2016)
EC 1.14.13.212 1,3,7-trimethyluric acid 5-monooxygenase (17 March 2016)
EC 1.14.13.213 bursehernin 5'-monooxygenase (17 March 2016)
EC 1.14.13.214 (–)-4'-demethyl-deoxypodophyllotoxin 4-hydroxylase (17 March 2016)
EC 1.14.13.215 protoasukamycin 4-monooxygenase (17 March 2016)
EC 1.14.13.216 asperlicin C monooxygenase (17 March 2016)
EC 1.14.13.217 protodeoxyviolaceinate monooxygenase (17 March 2016)
*EC 1.14.13.217 protodeoxyviolaceinate monooxygenase (28 September 2016)
EC 1.14.13.218 5-methylphenazine-1-carboxylate 1-monooxygenase (10 August 2016)
EC 1.14.13.219 resorcinol 4-hydroxylase (NADPH) (10 August 2016)
EC 1.14.13.220 resorcinol 4-hydroxylase (NADH) (10 August 2016)
EC 1.14.13.221 cholest-4-en-3-one 26-monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming] (10 August 2016)
EC 1.14.13.222 aurachin C monooxygenase/isomerase (28 September 2016)
EC 1.14.13.223 3-hydroxy-4-methylanthranilyl-[aryl-carrier protein] 5-monooxygenase (28 September 2016)
EC 1.14.13.224 violacein synthase (28 September 2016)
EC 1.14.13.225 F-actin monooxygenase (28 September 2016)
EC 1.14.13.226 acetone monooxygenase (methylacetate-forming) (28 September 2016)
EC 1.14.13.227 propane 2-monooxygenase (28 September 2016)
EC 1.14.13.228 jasmonic acid 12-hydroxylase (4 December 2016)
EC 1.14.13.229 tert-butyl alcohol monooxygenase (4 December 2016)
EC 1.14.13.230 butane monooxygenase (soluble) (4 December 2016)
EC 1.14.13.231 tetracycline 11a-monooxygenase (4 December 2016)
EC 1.14.13.232 6-methylpretetramide 4-monooxygenase (4 December 2016)
EC 1.14.13.233 4-hydroxy-6-methylpretetramide 12a-monooxygenase (4 December 2016)
EC 1.14.13.234 5a,11a-dehydrotetracycline 5-monooxygenase (4 December 2016)
*EC 1.14.14.3 bacterial luciferase (10 August 2016)
*EC 1.14.14.18 heme oxygenase (biliverdin-producing) (10 August 2016)
EC 1.14.14.20 phenol 2-monooxygenase (FADH2) (17 March 2016)
EC 1.14.14.21 dibenzothiophene monooxygenase (17 March 2016)
EC 1.14.14.22 dibenzothiophene sulfone monooxygenase (17 March 2016)
EC 1.14.14.23 cholesterol 7α-monooxygenase (17 March 2016)
EC 1.14.14.24 vitamin D 25-hydroxylase (17 March 2016)
EC 1.14.14.25 cholesterol 24-hydroxylase (17 March 2016)
EC 1.14.14.26 24-hydroxycholesterol 7α-hydroxylase (17 March 2016)
EC 1.14.14.27 resorcinol 4-hydroxylase (FADH2) (10 August 2016)
EC 1.14.14.28 long-chain alkane monooxygenase (10 August 2016)
EC 1.14.14.29 25/26-hydroxycholesterol 7α-hydroxylase (10 August 2016)
EC 1.14.14.30 isobutylamine N-monooxygenase (28 September 2016)
EC 1.14.14.31 ipsdienol synthase (28 September 2016)
EC 1.14.14.32 17α-hydroxyprogesterone deacetylase (28 September 2016)
EC 1.14.14.33 ethylenediaminetetraacetate monooxygenase (4 December 2016)
EC 1.14.14.34 methanesulfonate monooxygenase (FMNH2) (4 December 2016)
EC 1.14.14.35 dimethylsulfone monooxygenase (4 December 2016)
EC 1.14.14.36 tyrosine N-monooxygenase (4 December 2016)
EC 1.14.14.37 4-hydroxyphenylacetaldehyde oxime monooxygenase (4 December 2016)
*EC 1.14.15.9 spheroidene monooxygenase (17 March 2016)
EC 1.14.15.15 cholestanetriol 26-monooxygenase (17 March 2016)
EC 1.14.15.16 vitamin D3 24-hydroxylase (17 March 2016)
EC 1.14.15.17 pheophorbide-a oxygenase (17 March 2016)
EC 1.14.15.18 calcidiol 1-monooxygenase (10 August 2016)
EC 1.14.15.19 C-19 steroid 1α-hydroxylase (10 August 2016)
EC 1.14.15.20 heme oxygenase (biliverdin-producing, ferredoxin) (10 August 2016)
EC 1.14.15.21 zeaxanthin epoxidase (4 December 2016)
EC 1.14.15.22 vitamin D 1,25-hydroxylase (4 December 2016)
EC 1.14.19.48 tert-amyl alcohol desaturase (4 December 2016)
EC 1.14.19.49 tetracycline 7-halogenase (4 December 2016)
EC 1.14.19.50 noroxomaritidine synthase (4 December 2016)
*EC 1.14.21.2 (S)-cheilanthifoline synthase (4 December 2016)
EC 1.14.21.11 (–)-pluviatolide synthase (17 March 2016)
EC 1.14.21.12 (S)-nandinine synthase (28 September 2016)
EC 1.14.99.27 now EC 1.17.3.4 (4 December 2016)
EC 1.17.1.2 transferred now EC 1.17.7.4 (17 March 2016)
EC 1.17.3.4 juglone 3-hydroxylase (4 December 2016)
EC 1.17.7.4 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase (17 March 2016)
EC 1.17.8 With a flavin as acceptor (28 September 2016)
EC 1.17.8.1 hydroxysqualene dehydroxylase (28 September 2016)
EC 1.17.98.1 deleted (28 September 2016)
EC 1.17.98.2 bacteriochlorophyllide c C-71-hydroxylase (4 December 2016)
*EC 1.18.1.6 adrenodoxin-NADP+ reductase (17 March 2016)
EC 1.19.1 With NAD+ or NADP+ as acceptor (4 December 2016)
EC 1.19.1.1 flavodoxin—NADP+ reductase (4 December 2016)
EC 1.21.3.9 transferred now EC 1.21.98.2 (17 March 2016)
EC 1.21.98.2 dichlorochromopyrrolate synthase (17 March 2016)
EC 1.21.98.3 anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase (4 December 2016)
*EC 2.1.1.47 indolepyruvate C-methyltransferase (28 September 2016)
EC 2.1.1.323 (–)-pluviatolide 4-O-methyltransferase (17 March 2016)
EC 2.1.1.324 dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose N,N-dimethyltransferase (17 March 2016)
EC 2.1.1.325 juvenile hormone-III synthase (10 August 2016)
EC 2.1.1.326 N-acetyl-demethylphosphinothricin P-methyltransferase (10 August 2016)
EC 2.1.1.327 phenazine-1-carboxylate N-methyltransferase (28 September 2016)
EC 2.1.1.328 N-demethylindolmycin N-methyltransferase (28 September 2016)
EC 2.1.1.329 demethylphylloquinol methyltransferase (4 December 2016)
EC 2.1.1.330 5'-demethylyatein 5'-O-methyltransferase (4 December 2016)
EC 2.1.1.331 bacteriochlorophyllide d C-121-methyltransferase (4 December 2016)
EC 2.1.1.332 bacteriochlorophyllide d C-82-methyltransferase (4 December 2016)
EC 2.1.1.333 bacteriochlorophyllide d C-20 methyltransferase (4 December 2016)
EC 2.1.1.334 methanethiol S-methyltransferase (4 December 2016)
EC 2.1.1.335 4-amino-anhydrotetracycline N4-methyltransferase (4 December 2016)
EC 2.1.1.336 norbelladine O-methyltransferase (4 December 2016)
EC 2.3.1.88 now covered by EC 2.3.1.254, EC 2.3.1.255, EC 2.3.1.256, EC 2.3.1.257, EC 2.3.1.258, EC 2.3.1.259 (4 December 2016)
*EC 2.3.1.111 mycocerosate synthase (17 March 2016)
*EC 2.4.1.135 galactosylgalactosylxylosylprotein 3-β-glucuronosyltransferase (28 September 2016)
*EC 2.3.1.161 lovastatin nonaketide synthase (10 August 2016)
*EC 2.3.1.181 lipoyl(octanoyl) transferase (17 March 2016)
*EC 2.3.1.244 2-methylbutanoate polyketide synthase (4 December 2016)
EC 2.3.1.253 phloroglucinol synthase (4 December 2016)
EC 2.3.1.254 N-terminal methionine Nα-acetyltransferase NatB (4 December 2016)
EC 2.3.1.255 N-terminal amino-acid Nα-acetyltransferase NatA (4 December 2016)
EC 2.3.1.256 N-terminal methionine Nα-acetyltransferase NatC (4 December 2016)
EC 2.3.1.257 N-terminal L-serine Nα-acetyltransferase NatD (4 December 2016)
EC 2.3.1.258 N-terminal methionine Nα-acetyltransferase NatE (4 December 2016)
EC 2.3.1.259 N-terminal methionine Nα-acetyltransferase NatF (4 December 2016)
EC 2.3.1.260 tetracycline polyketide synthase (4 December 2016)
*EC 2.3.2.6 lysine/arginine leucyltransferase (4 December 2016)
EC 2.3.2.29 aspartate/glutamate leucyltransferase (4 December 2016)
EC 2.3.3.17 methylthioalkylmalate synthase (4 December 2016)
EC 2.4.1.45 now included with EC 2.4.1.47 (4 December 2016)
*EC 2.4.1.122 N-acetylgalactosaminide β-1,3-galactosyltransferase (4 December 2016)
*EC 2.4.1.149 N-acetyllactosaminide β-1,3-N-acetylglucosaminyltransferase (4 December 2016)
EC 2.4.1.163 now included with EC 2.4.1.149 (4 December 2016)
*EC 2.4.1.187 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-β-D-mannosaminyltransferase (28 September 2016)
*EC 2.4.1.223 glucuronosyl-galactosyl-proteoglycan 4-α-N-acetylglucosaminyltransferase (4 December 2016)
EC 2.3.1.252 mycolipanoate synthase (10 August 2016)
*EC 2.4.1.264 D-Man-α-(1→3)-D-Glc-β-(1→4)-D-Glc-α-1-diphosphoundecaprenol 2-β-glucuronosyltransferase (4 December 2016)
*EC 2.4.1.302 L-demethylnoviosyl transferase (17 March 2016)
EC 2.4.1.307 now included with EC 2.4.1.122 (4 December 2016)
EC 2.4.1.342 α-maltose-1-phosphate synthase (4 December 2016)
EC 2.4.1.338 validoxylamine A glucosyltransferase (10 August 2016)
EC 2.4.1.339 β-1,2-mannobiose phosphorylase (10 August 2016)
EC 2.4.1.340 1,2-β-oligomannan phosphorylase (10 August 2016)
EC 2.4.1.341 α-1,2-colitosyltransferase (10 August 2016)
*EC 2.4.2.26 protein xylosyltransferase (4 December 2016)
EC 2.4.2.58 hydroxyproline O-arabinosyltransferase (10 August 2016)
EC 2.4.99.11 now included with EC 2.4.99.1 (4 December 2016)
*EC 2.5.1.38 isonocardicin synthase (4 December 2016)
EC 2.5.1.132 3-deoxy-D-glycero-D-galacto-nononate 9-phosphate synthase (10 August 2016)
EC 2.5.1.133 bacteriochlorophyll a synthase (28 September 2016)
EC 2.5.1.134 cystathionine β-synthase (O-acetyl-L-serine) (28 September 2016)
EC 2.5.1.135 validamine 7-phosphate valienyltransferase (4 December 2016)
EC 2.6.1.68 deleted, covered by EC 2.6.1.13 and EC 2.6.1.36 (10 August 2016)
EC 2.6.1.110 dTDP-4-dehydro-2,3,6-trideoxy-D-glucose 4-aminotransferase (17 March 2016)
*EC 2.7.1.27 erythritol kinase (D-erythritol 4-phosphate-forming) (28 September 2016)
EC 2.7.1.69 transferred to EC 2.7.1.191 to EC 2.7.1.208 (17 March 2016)
*EC 2.7.1.91 sphingosine kinase (28 September 2016)
EC 2.7.1.191 protein-Nπ-phosphohistidine—D-mannose phosphotransferase (17 March 2016)
EC 2.7.1.192 protein-Nπ-phosphohistidine—N-acetylmuramate phosphotransferase (17 March 2016)
EC 2.7.1.193 protein-Nπ-phosphohistidine—N-acetyl-D-glucosamine phosphotransferase (17 March 2016)
EC 2.7.1.194 protein-Nπ-phosphohistidine—L-ascorbate phosphotransferase (17 March 2016)
EC 2.7.1.195 protein-Nπ-phosphohistidine—2-O-α-mannosyl-D-glycerate phosphotransferase (17 March 2016)
EC 2.7.1.196 protein-Nπ-phosphohistidine—N,N'-diacetylchitobiose phosphotransferase (17 March 2016)
EC 2.7.1.197 protein-Nπ-phosphohistidine—D-mannitol phosphotransferase (17 March 2016)
EC 2.7.1.198 protein-Nπ-phosphohistidine—D-sorbitol phosphotransferase (17 March 2016)
EC 2.7.1.199 protein-Nπ-phosphohistidine—D-glucose phosphotransferase (17 March 2016)
EC 2.7.1.200 protein-Nπ-phosphohistidine—galactitol phosphotransferase (17 March 2016)
EC 2.7.1.201 protein-Nπ-phosphohistidine—trehalose phosphotransferase (17 March 2016)
EC 2.7.1.202 protein-Nπ-phosphohistidine—D-fructose phosphotransferase (17 March 2016)
EC 2.7.1.203 protein-Nπ-phosphohistidine—D-glucosaminate phosphotransferase (17 March 2016)
EC 2.7.1.204 protein-Nπ-phosphohistidine—D-galactose phosphotransferase (17 March 2016)
EC 2.7.1.205 protein-Nπ-phosphohistidine—D-cellobiose phosphotransferase (17 March 2016)
EC 2.7.1.206 protein-Nπ-phosphohistidine—L-sorbose phosphotransferase (17 March 2016)
EC 2.7.1.207 protein-Nπ-phosphohistidine—lactose phosphotransferase (17 March 2016)
EC 2.7.1.208 protein-Nπ-phosphohistidine—maltose phosphotransferase (17 March 2016)
EC 2.7.1.209 L-erythrulose 4-kinase (10 August 2016)
EC 2.7.1.210 D-erythrulose 4-kinase (10 August 2016)
EC 2.7.1.211 protein-Nπ-phosphohistidine—sucrose phosphotransferase (28 September 2016)
EC 2.7.1.212 α-D-ribose-1-phosphate 5-kinase (ADP) (28 September 2016)
EC 2.7.1.213 cytidine kinase (28 September 2016)
EC 2.7.1.214 C7-cyclitol 7-kinase (28 September 2016)
EC 2.7.1.215 erythritol kinase (D-erythritol 1-phosphate-forming) (28 September 2016)
*EC 2.7.4.7 phosphooxymethylpyrimidine kinase (28 September 2016)
EC 2.7.4.30 now EC 2.7.8.43 (4 December 2016)
*EC 2.7.7.35 ADP ribose phosphorylase (4 December 2016)
*EC 2.7.7.42 [glutamine synthetase] adenylyltransferase (28 September 2016)
EC 2.7.7.63 transferred now EC 6.3.1.20 (17 March 2016)
*EC 2.7.7.89 [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase (28 September 2016)
EC 2.7.7.90 CMP-8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase (17 March 2016)
EC 2.7.7.91 valienol-1-phosphate guanylyltransferase (28 September 2016)
EC 2.7.7.92 3-deoxy-D-glycero-D-galacto-nononate cytidylyltransferase (28 September 2016)
EC 2.7.7.93 phosphonoformate cytidylyltransferase (28 September 2016)
EC 2.7.7.94 4-hydroxyphenylalkanoate adenylyltransferase (28 September 2016)
EC 2.7.7.95 mycocerosic acid adenylyltransferase (4 December 2016)
EC 2.7.7.96 ADP-D-ribose pyrophosphorylase (4 December 2016)
EC 2.7.7.97 3-hydroxy-4-methylanthranilate adenylyltransferase (4 December 2016)
*EC 2.7.8.5 CDP-diacylglycerol—glycerol-3-phosphate 1-phosphatidyltransferase (28 September 2016)
EC 2.7.8.43 lipid A phosphoethanolamine transferase (4 December 2016)
EC 2.7.8.44 teichoic acid glycerol-phosphate primase (4 December 2016)
*EC 2.8.1.10 thiazole synthase (28 September 2016)
*EC 2.8.1.11 molybdopterin synthase sulfurtransferase (28 September 2016)
EC 2.8.3.24 (R)-2-hydroxy-4-methylpentanoate CoA-transferase (10 August 2016)
EC 2.8.3.25 bile acid CoA-transferase (28 September 2016)
EC 3.1.1.99 6-deoxy-6-sulfogluconolactonase (17 March 2016)
EC 3.1.1.100 chlorophyllide a hydrolase (28 September 2016)
EC 3.1.1.101 poly(ethylene terephthalate) hydrolase (28 September 2016)
EC 3.1.1.102 mono(ethylene terephthalate) hydrolase (28 September 2016)
EC 3.1.2.26 transferred now EC 2.8.3.25 (28 September 2016)
EC 3.1.2.32 2-aminobenzoylacetyl-CoA thioesterase (28 September 2016)
EC 3.1.3.13 deleted now covered by EC 5.4.2.11 (28 September 2016)
EC 3.1.3.98 now EC 3.6.1.68 (4 December 2016)
EC 3.1.3.99 IMP-specific 5'-nucleotidase (17 March 2016)
EC 3.1.3.100 thiamine phosphate phosphatase (17 March 2016)
EC 3.1.3.101 validoxylamine A 7'-phosphate phosphatase (10 August 2016)
EC 3.1.3.102 FMN hydrolase (10 August 2016)
EC 3.1.3.103 3-deoxy-D-glycero-D-galacto-nononate 9-phosphatase (28 September 2016)
EC 3.1.3.104 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase (28 September 2016)
*EC 3.2.1.179 gellan tetrasaccharide unsaturated glucuronosyl hydrolase (4 December 2016)
EC 3.2.1.196 limit dextrin α-1,6-maltotetraose-hydrolase (17 March 2016)
EC 3.2.1.197 β-1,2-mannosidase (28 September 2016)
EC 3.2.1.198 α-mannan endo-1,2-α-mannanase (28 September 2016)
EC 3.2.1.199 sulfoquinovosidase (28 September 2016)
*EC 3.3.2.2 lysoplasmalogenase (4 December 2016)
EC 3.3.2.5 transferred now covered by EC 3.3.2.2 (28 September 2016)
EC 3.3.2.15 trans-2,3-dihydro-3-hydroxyanthranilic acid synthase (10 August 2016)
EC 3.4.19.15 desampylase (4 December 2016)
EC 3.4.24.88 now EC 3.4.19.15 (4 December 2016)
EC 3.5.1.120 2-aminomuconate deaminase (2-hydroxymuconate-forming) (10 August 2016)
EC 3.5.1.121 protein N-terminal asparagine amidohydrolase (4 December 2016)
EC 3.5.1.122 protein N-terminal glutamine amidohydrolase (4 December 2016)
EC 3.5.1.123 γ-glutamylanilide hydrolase (4 December 2016)
EC 3.5.1.124 protein deglycase (4 December 2016)
EC 3.5.4.42 N-isopropylammelide isopropylaminohydrolase (10 August 2016)
EC 3.5.4.43 hydroxydechloroatrazine ethylaminohydrolase (28 September 2016)
EC 3.5.99.3 transferred now EC 3.5.4.43 (28 September 2016)
EC 3.5.99.4 transferred, now EC 3.5.4.42 (10 August 2016)
*EC 3.6.1.9 nucleotide diphosphatase (10 August 2016)
EC 3.6.1.19 transferred, now included in *EC 3.6.1.9 (10 August 2016)
EC 3.6.1.68 geranyl diphosphate phosphohydrolase (4 December 2016)
EC 3.7.1.23 maleylpyruvate hydrolase (17 March 2016)
EC 3.9.1.3 phosphohistidine phosphatase (17 March 2016)
EC 4.1.1.103 γ-resorcylate decarboxylase (28 September 2016)
EC 4.1.2.30 transferred now EC 1.14.14.32 (28 September 2016)
EC 4.1.2.58 2-dehydro-3,6-dideoxy-6-sulfogluconate aldolase (17 March 2016)
EC 4.1.99.18 transferred now EC 4.1.99.22 and EC 4.6.1.17 (28 September 2016)
*EC 4.1.99.20 3-amino-4-hydroxybenzoate synthase (28 September 2016)
EC 4.1.99.22 GTP 3',8-cyclase (28 September 2016)
*EC 4.2.1.1 carbonic anhydrase (4 December 2016)
*EC 4.2.1.106 bile-acid 7α-dehydratase (10 August 2016)
EC 4.2.1.162 6-deoxy-6-sulfo-D-gluconate dehydratase (17 March 2016)
EC 4.2.1.163 2-oxo-hept-4-ene-1,7-dioate hydratase (17 March 2016)
EC 4.2.1.164 dTDP-4-dehydro-2,6-dideoxy-D-glucose 3-dehydratase (10 August 2016)
EC 4.2.1.165 chlorophyllide a 31-hydratase (10 August 2016)
EC 4.2.1.166 phosphinomethylmalate isomerase (10 August 2016)
EC 4.2.1.167 (R)-2-hydroxyglutaryl-CoA dehydratase (10 August 2016)
EC 4.2.1.168 GDP-4-dehydro-6-deoxy-α-D-mannose 3-dehydratase (28 September 2016)
EC 4.2.1.169 3-vinyl bacteriochlorophyllide d 31-hydratase (4 December 2016)
EC 4.2.1.170 2-(ω-methylthio)alkylmalate dehydratase (4 December 2016)
*EC 4.2.3.152 2-epi-5-epi-valiolone synthase (10 August 2016)
EC 4.2.3.154 demethyl-4-deoxygadusol synthase (10 August 2016)
EC 4.2.3.155 2-epi-valiolone synthase (10 August 2016)
EC 4.2.3.156 hydroxysqualene synthase (28 September 2016)
EC 4.2.99.23 tuliposide B-converting enzyme (17 March 2016)
EC 4.3.1.31 L-tryptophan ammonia lyase (10 August 2016)
EC 4.4.1.34 isoprene-epoxide—glutathione S-transferase (28 September 2016)
EC 4.6.1.17 cyclic pyranopterin monophosphate synthase (28 September 2016)
*EC 4.7.1.1 α-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase (4 December 2016)
*EC 4.99.1.1 protoporphyrin ferrochelatase (28 September 2016)
EC 4.99.1.9 coproporphyrin ferrochelatase (10 August 2016)
*EC 5.1.1.14 nocardicin A epimerase (10 August 2016)
EC 5.1.3.38 D-erythrulose 1-phosphate 3-epimerase (10 August 2016)
EC 5.1.3.39 L-erythrulose 4-phosphate epimerase (10 August 2016)
EC 5.3.1.33 L-erythrulose 1-phosphate isomerase (10 August 2016)
EC 5.3.1.34 D-erythrulose 4-phosphate isomerase (10 August 2016)
EC 5.3.3.20 2-hydroxyisobutanoyl-CoA mutase (10 August 2016)
*EC 6.2.1.19 long-chain-fatty-acid—protein ligase (28 September 2016)
EC 6.2.1.47 medium-chain-fatty-acid—[acyl-carrier-protein] ligase (28 September 2016)
*EC 6.3.1.2 glutamine synthetase (28 September 2016)
EC 6.3.1.20 lipoate—protein ligase (17 March 2016)
*EC 6.5.1.1 DNA ligase (ATP) (28 September 2016)
*EC 6.5.1.2 DNA ligase (NAD+) (4 December 2016)
*EC 6.5.1.3 RNA ligase (ATP) (28 September 2016)
*EC 6.5.1.4 RNA 3'-terminal-phosphate cyclase (ATP) (4 December 2016)
*EC 6.5.1.5 RNA 3'-terminal-phosphate cyclase (GTP) (4 December 2016)
*EC 6.5.1.6 DNA ligase (ATP or NAD+) (4 December 2016)
*EC 6.5.1.7 DNA ligase (ATP, ADP or GTP) (4 December 2016)
*EC 6.3.2.47 dapdiamide synthase (10 August 2016)