New enzymes (12 March 2017, approved 29 March 2017)The entries were added on the date indicated and fully approved after a month. An asterisk before 'EC' indicates that this is an amendment to an existing enzyme rather than a new enzyme entry.
New enzymes (7 June 2017, approved 5 July 2017)
New enzymes (13 October 2017, approved 10 November 2017)
New enzymes (15 December 2017, approved 15 January 2018)
*EC 1.1.1.137 ribitol-5-phosphate 2-dehydrogenase (12 March 2017)
*EC 1.1.1.348 (3R)-2'-hydroxyisoflavanone reductase (13 October 2017)
EC 1.1.1.404 tetrachlorobenzoquinone reductase (12 March 2017)
EC 1.1.1.405 ribitol-5-phosphate 2-dehydrogenase (NADP+) (12 March 2017)
EC 1.1.1.406 galactitol 2-dehydrogenase (L-tagatose-forming) (12 March 2017)
EC 1.1.1.407 D-altritol 5-dehydrogenase (12 March 2017)
EC 1.1.1.408 4-phospho-D-threonate 3-dehydrogenase (7 June 2017)
EC 1.1.1.409 4-phospho-D-erythronate 3-dehydrogenase (7 June 2017)
EC 1.1.1.410 D-erythronate 2-dehydrogenase (7 June 2017)
EC 1.1.1.411 L-threonate 2-dehydrogenase (7 June 2017)
EC 1.1.1.412 2-alkyl-3-oxoalkanoate reductase (13 October 2017)
EC 1.1.1.413 A-factor type γ-butyrolactone 1'-reductase (1S-forming) (13 October 2017)
EC 1.1.5.6 transferred now EC 1.17.5.3 (13 October 2017)
EC 1.1.99.33 transferred now EC 1.17.99.7 (13 October 2017)
EC 1.1.99.41 3-hydroxy-1,2-didehydro-2,3-dihydrotabersonine reductase (13 October 2017)
EC 1.2.1.99 4-(γ-glutamylamino)butanal dehydrogenase (7 June 2017)
EC 1.2.7.12 formylmethanofuran dehydrogenase (7 June 2017)
EC 1.2.99.5 transferred, now EC 1.2.7.12 (7 June 2017)
EC 1.1.5.12 D-lactate dehydrogenase (quinone) (12 March 2017)
EC 1.1.98.6 ribonucleoside-triphosphate reductase (formate) (12 March 2017)
EC 1.1.99.40 (R)-2-hydroxyglutarate—pyruvate transhydrogenase (12 March 2017)
EC 1.2.1.2 transferred now EC 1.17.1.9 (13 October 2017)
EC 1.2.1.43 transferred now EC 1.17.1.10 (13 October 2017)
EC 1.2.1.93 transferred now EC 1.17.1.11 (13 October 2017)
EC 1.2.2.3 transferred now EC 1.17.2.3 (13 October 2017)
EC 1.2.99.9 transferred now EC 1.17.98.3 (13 October 2017)
EC 1.2.99.10 4,4'-diapolycopenoate synthase (15 December 2017)
EC 1.3.1.113 (4-alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate reductase (15 December 2017)
EC 1.3.8.13 crotonobetainyl-CoA reductase (12 March 2017)
EC 1.3.8.14 L-prolyl-S-[peptidyl-carrier protein] dehydrogenase (15 December 2017)
EC 1.3.99.38 menaquinone-9 β-reductase (12 March 2017)
*EC 1.4.1.12 2,4-diaminopentanoate dehydrogenase (12 March 2017)
EC 1.4.1.25 L-arginine dehydrogenase (12 March 2017)
EC 1.4.1.26 2,4-diaminopentanoate dehydrogenase (NAD+) (12 March 2017)
EC 1.4.3.25 L-arginine oxidase (12 March 2017)
*EC 1.4.99.6 D-arginine dehydrogenase (12 March 2017)
EC 1.5.1.51 N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate dehydrogenase (12 March 2017)
EC 1.5.5.3 hydroxyproline dehydrogenase (13 October 2017)
EC 1.5.98.3 coenzyme F420:methanophenazine dehydrogenase (13 October 2017)
*EC 1.5.8.4 dimethylglycine dehydrogenase (7 June 2017)
EC 1.7.1.16 nitrobenzene nitroreductase (7 June 2017)
EC 1.7.99.4 transferred, now EC 1.7.1.1, EC 1.7.1.2, EC 1.7.1.3, EC 1.7.5.1, EC 1.7.7.2 and EC 1.9.6.1 (7 June 2017)
EC 1.8.1.20 4,4'-dithiodibutanoate disulfide reductase (13 October 2017)
EC 1.8.2.5 thiosulfate reductase (cytochrome) (12 March 2017)
EC 1.8.3.7 formylglycine-generating enzyme (13 October 2017)
*EC 1.8.5.4 bacterial sulfide:quinone reductase (15 December 2017)
*EC 1.8.5.5 thiosulfate reductase (quinone) (15 December 2017)
EC 1.8.5.7 glutathionyl-hydroquinone reductase (12 March 2017)
EC 1.8.5.8 eukaryotic sulfide quinone oxidoreductase (15 December 2017)
EC 1.8.7.3 ferredoxin:CoB-CoM heterodisulfide reductase (15 December 2017)
*EC 1.8.98.1 dihydromethanophenazine:CoB-CoM heterodisulfide reductase (15 December 2017)
EC 1.8.98.4 coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase (15 December 2017)
EC 1.8.98.5 H2:CoB-CoM heterodisulfide,ferredoxin reductase (15 December 2017)
EC 1.8.98.6 formate:CoB-CoM heterodisulfide,ferredoxin reductase (15 December 2017)
*EC 1.10.3.14 ubiquinol oxidase (electrogenic, non H+-transporting) (13 October 2017)
EC 1.13.11.83 4-hydroxy-3-prenylphenylpyruvate oxygenase (13 October 2017)
EC 1.13.11.84 crocetin dialdehyde synthase (15 December 2017)
*EC 1.13.12.5 Renilla-type luciferase (13 October 2017)
*EC 1.13.12.7 firefly luciferase (15 December 2017)
EC 1.13.12.23 4-hydroxy-3-prenylbenzoate synthase (13 October 2017)
*EC 1.14.11.7 procollagen-proline 3-dioxygenase (15 December 2017)
*EC 1.14.11.19 anthocyanidin synthase (12 March 2017)
EC 1.14.11.55 ectoine hydroxylase (12 March 2017)
EC 1.14.11.56 L-proline cis-4-hydroxylase (12 March 2017)
EC 1.14.11.57 L-proline trans-4-hydroxylase (12 March 2017)
*EC 1.14.13.39 nitric-oxide synthase (NADPH) (7 June 2017)
EC 1.14.13.48 transferred now EC 1.14.14.51 (13 October 2017)
EC 1.14.13.49 transferred now EC 1.14.14.52 (13 October 2017)
EC 1.14.13.72 transferred now EC 1.14.18.9 (13 October 2017)
*EC 1.14.13.50 pentachlorophenol monooxygenase (12 March 2017)
EC 1.14.13.67 transferred now EC 1.14.14.55 (15 December 2017)
EC 1.14.13.80 transferred now EC 1.14.14.53 (13 October 2017)
*EC 1.14.13.81 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase (12 March 2017)
EC 1.14.13.117 transferred now EC 1.14.14.39 (12 March 2017)
EC 1.14.13.118 transferred now EC 1.14.14.38 (12 March 2017)
EC 1.14.13.124 transferred now EC 1.14.14.40 (12 March 2017)
EC 1.14.13.129 transferred now EC 1.14.15.24 (15 December 2017)
EC 1.14.13.157 transferred now EC 1.14.14.56 (15 December 2017)
EC 1.14.13.165 transferred, now EC 1.14.14.47 (7 June 2017)
EC 1.14.13.235 indole-3-acetate monooxygenase (7 June 2017)
EC 1.14.13.236 toluene 4-monooxygenase (7 June 2017)
EC 1.14.13.239 carnitine monooxygenase (15 December 2017)
*EC 1.14.11.2 procollagen-proline 4-dioxygenase (13 October 2017)
EC 1.14.13.237 aliphatic glucosinolate S-oxygenase (13 October 2017)
EC 1.14.13.238 dimethylamine monooxygenase (13 October 2017)
*EC 1.14.14.30 isobutylamine N-monooxygenase (7 June 2017)
EC 1.14.14.38 valine N-monooxygenase (12 March 2017)
EC 1.14.14.39 isoleucine N-monooxygenase (12 March 2017)
EC 1.14.14.40 phenylalanine N-monooxygenase (12 March 2017)
EC 1.14.14.41 (E)-2-methylbutanal oxime monooxygenase (12 March 2017)
EC 1.14.14.42 homomethionine N-monooxygenase (12 March 2017)
EC 1.14.14.43 (methylthio)alkanaldoxime N-monooxygenase (12 March 2017)
EC 1.14.14.44 phenylacetaldehyde oxime monooxygenase (7 June 2017)
EC 1.14.14.45 aromatic aldoxime N-monooxygenase (7 June 2017)
EC 1.14.14.46 pimeloyl-[acyl-carrier protein] synthase (7 June 2017)
EC 1.14.14.47 nitric-oxide synthase (flavodoxin) (7 June 2017)
EC 1.14.14.48 jasmonoyl-L-amino acid 12-hydroxylase (13 October 2017)
EC 1.14.14.49 12-hydroxyjasmonoyl-L-amino acid 12-hydroxylase (13 October 2017)
EC 1.14.14.50 tabersonine 3-oxygenase (13 October 2017) (13 October 2017)
EC 1.14.14.51 (S)-limonene 6-monooxygenase (13 October 2017)
EC 1.14.14.52 (S)-limonene 7-monooxygenase (13 October 2017)
EC 1.14.14.53 (R)-limonene 6-monooxygenase (13 October 2017)
EC 1.14.14.54 phenylacetate 2-hydroxylase (13 October 2017)
EC 1.14.14.55 quinine 3-monooxygenase (15 December 2017)
EC 1.14.14.56 1,8-cineole 2-exo-monooxygenase (15 December 2017)
EC 1.14.15.12 transferred, now EC 1.14.14.46 (7 June 2017)
EC 1.14.15.23 chloroacetanilide N-alkylformylase (13 October 2017)
EC 1.14.15.24 β-carotene 3-hydroxylase (15 December 2017)
EC 1.14.18.9 methylsterol monooxygenase (13 October 2017)
EC 1.14.19.51 (S)-corytuberine synthase (7 June 2017)
EC 1.14.19.52 camalexin synthase (13 October 2017)
EC 1.14.99.42 transferred now EC 1.13.11.84 (15 December 2017)
*EC 1.14.99.48 heme oxygenase (staphylobilin-producing) (12 March 2017)
EC 1.14.99.53 lytic chitin monoxygenase (12 March 2017)
EC 1.14.99.54 lytic cellulose monooxygenase (C1-hydroxylating) (7 June 2017)
EC 1.14.99.55 lytic starch monooxygenase (7 June 2017)
EC 1.14.99.56 lytic cellulose monooxygenase (C4-dehydrogenating) (7 June 2017)
EC 1.14.99.57 heme oxygenase (mycobilin-producing) (7 June 2017)
EC 1.14.99.58 heme oxygenase (biliverdin-IX-β and δ-forming) (13 October 2017)
EC 1.14.99.59 tryptamine 4-monooxygenase (15 December 2017)
EC 1.16.3.3 manganese oxidase (13 October 2017)
EC 1.17.1.9 formate dehydrogenase (13 October 2017)
EC 1.17.1.10 formate dehydrogenase (NADP+)
EC 1.17.1.11 formate dehydrogenase (NAD+, ferredoxin) (13 October 2017)
EC 1.17.2.3 formate dehydrogenase (cytochrome-c-553) (13 October 2017)
*EC 1.17.4.1 ribonucleoside-diphosphate reductase (12 March 2017)
*EC 1.17.4.2 ribonucleoside-triphosphate reductase (thioredoxin) (12 March 2017)
EC 1.17.5.3 formate dehydrogenase-N (13 October 2017)
*EC 1.17.98.2 bacteriochlorophyllide c C-71-hydroxylase (7 June 2017)
EC 1.17.98.3 formate dehydrogenase (coenzyme F420) (13 October 2017)
EC 1.17.99.7 formate dehydrogenase (acceptor) (13 October 2017)
EC 1.21.99.5 tetrachloroethene reductive dehalogenase (12 March 2017)
EC 1.97.1.8 transferred now EC 1.21.99.5 (12 March 2017)
*EC 2.1.1.63 methylated-DNA—[protein]-cysteine S-methyltransferase (7 June 2017)
*EC 2.1.1.86 tetrahydromethanopterin S-methyltransferase (7 June 2017)
EC 2.1.1.337 reticuline N-methyltransferase (12 March 2017)
EC 2.1.1.338 desmethylxanthohumol 6'-O-methyltransferase (12 March 2017)
EC 2.1.1.339 xanthohumol 4'-O-methyltransferase (12 March 2017)
EC 2.1.1.340 3-aminomethylindole N-methyltransferase (7 June 2017)
EC 2.1.1.341 vanillate/3-O-methylgallate O-demethylase (7 June 2017)
EC 2.1.1.342 anaerobilin synthase (7 June 2017)
EC 2.1.1.343 8-amino-8-demethylriboflavin N,N-dimethyltransferase (13 October 2017)
EC 2.1.1.344 ornithine lipid N-methyltransferase (13 October 2017)
EC 2.1.1.345 psilocybin synthase (15 December 2017)
EC 2.1.3.15 acetyl-CoA carboxytransferase (15 December 2017)
*EC 2.3.1.48 histone acetyltransferase (12 March 2017)
*EC 2.3.1.111 mycocerosate synthase (7 June 2017)
*EC 2.3.1.230 2-heptyl-4(1H)-quinolone synthase (12 March 2017)
EC 2.3.1.261 4-hydroxyphenylalkanoate synthase (12 March 2017)
EC 2.3.1.262 anthraniloyl-CoA anthraniloyltransferase (12 March 2017)
EC 2.3.1.263 2-amino-4-oxopentanoate thiolase (12 March 2017)
EC 2.3.1.264 β-lysine N6-acetyltransferase (7 June 2017)
EC 2.3.1.265 phosphatidylinositol dimannoside acyltransferase (13 October 2017)
EC 2.3.2.4 transferred now EC 4.3.2.9 (13 October 2017)
*EC 2.3.2.26 HECT-type E3 ubiquitin transferase (15 December 2017)
*EC 2.3.2.27 RING-type E3 ubiquitin transferase (15 December 2017)
EC 2.3.2.30 L-ornithine Nα-acyltransferase (13 October 2017)
EC 2.3.2.31 RBR-type E3 ubiquitin transferase (15 December 2017)
EC 2.3.2.32 cullin-RING-type E3 NEDD8 transferase (15 December 2017)
EC 2.3.3.18 2-phosphinomethylmalate synthase (12 March 2017)
EC 2.3.3.19 2-phosphonomethylmalate synthase (7 June 2017)
*EC 2.4.1.52 poly(glycerol-phosphate) α-glucosyltransferase (13 October 2017)
EC 2.4.1.57 deleted now covered by EC 2.4.1.345 and EC 2.4.1.346 (7 June 2017)
*EC 2.4.1.69 type 1 galactoside α-(1,2)-fucosyltransferase (12 March 2017)
*EC 2.4.1.86 N-acetyl-β-D-glucosaminide β-(1,3)-galactosyltransferase (7 June 2017)
*EC 2.4.1.150 N-acetyllactosaminide β-1,6-N-acetylglucosaminyltransferase (13 October 2017)
EC 2.4.1.164 transferred now EC 2.4.1.150 (13 October 2017)
*EC 2.4.1.287 rhamnopyranosyl-N-acetylglucosaminyl-diphospho-decaprenol β-1,4/1,5-galactofuranosyltransferase (12 March 2017)
*EC 2.4.1.303 UDP-Gal:α-D-GlcNAc-diphosphoundecaprenol β-1,3-galactosyltransferase (12 March 2017)
EC 2.4.1.343 UDP-Gal:α-D-GlcNAc-diphosphoundecaprenol α-1,3-galactosyltransferase (12 March 2017)
EC 2.4.1.344 type 2 galactoside α-(1,2)-fucosyltransferase (12 March 2017)
EC 2.4.1.345 phosphatidyl-myo-inositol α-mannosyltransferase (7 June 2017)
EC 2.4.1.346 phosphatidyl-myo-inositol dimannoside synthase (7 June 2017)
EC 2.4.1.347 α,α-trehalose-phosphate synthase (ADP-forming) (13 October 2017)
EC 2.4.1.348 N-acetyl-α-D-glucosaminyl-diphospho-ditrans
octacis-undecaprenol 3-α-mannosyltransferase (15 December 2017)
EC 2.4.1.349 mannosyl-N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 3-α-mannosyltransferase (15 December 2017)
EC 2.4.1.350 mogroside IE synthase (15 December 2017)
*EC 2.4.99.1 β-galactoside α-(2,6)-sialyltransferase (12 March 2017)
*EC 2.4.99.2 β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminide α-2,3-sialyltransferase (7 June 2017)
*EC 2.4.99.6 N-acetyllactosaminide α-2,3-sialyltransferase (12 March 2017)
EC 2.4.99.10 transferred now included with EC 2.4.99.6 (12 March 2017)
EC 2.5.1.136 2-acylphloroglucinol 4-prenyltransferase (12 March 2017)
EC 2.5.1.137 2-acyl-4-prenylphloroglucinol 6-prenyltransferase (12 March 2017)
EC 2.5.1.138 coumarin 8-geranyltransferase (12 March 2017)
EC 2.5.1.139 umbelliferone 6-dimethylallyltransferase (12 March 2017)
EC 2.5.1.140 N-(2-amino-2-carboxyethyl)-L-glutamate synthase (7 June 2017)
EC 2.5.1.141 heme o synthase (13 October 2017)
EC 2.5.1.142 nerylneryl diphosphate synthase (15 December 2017)
*EC 2.6.1.82 putrescine—2-oxoglutarate transaminase (7 June 2017)
EC 2.6.1.111 3-aminobutanoyl-CoA transaminase (12 March 2017)
EC 2.6.1.112 (S)-ureidoglycine—glyoxylate transaminase (12 March 2017)
EC 2.6.1.113 putrescine—pyruvate transaminase (7 June 2017)
*EC 2.7.1.181 polymannosyl GlcNAc-diphospho-ditrans,octacis-undecaprenol kinase (15 December 2017)
EC 2.7.1.216 farnesol kinase (12 March 2017)
EC 2.7.1.217 3-dehydrotetronate 4-kinase (7 June 2017)
EC 2.7.1.218 fructoselysine 6-kinase (13 October 2017)
EC 2.7.1.219 D-threonate 4-kinase (13 October 2017)
EC 2.7.1.220 D-erythronate 4-kinase (13 October 2017)
EC 2.7.1.221 N-acetylmuramate 1-kinase (13 October 2017)
EC 2.7.1.222 4-hydroxytryptamine kinase (15 December 2017)
EC 2.7.3.13 glutamine kinase (15 December 2017)
EC 2.7.4.32 farnesyl phosphate kinase (12 March 2017)
EC 2.7.7.94 transferred now EC 6.2.1.51 (15 December 2017)
EC 2.7.7.95 transferred, now EC 6.2.1.49, (7 June 2017)
EC 2.7.7.98 4-hydroxybenzoate adenylyltransferase (12 March 2017)
EC 2.7.7.98 transferred now EC 6.2.1.50 (13 October 2017)
EC 2.7.7.99 N-acetyl-α-D-muramate 1-phosphate uridylyltransferase (13 October 2017)
*EC 2.7.8.12 teichoic acid poly(glycerol phosphate) polymerase (12 March 2017)
*EC 2.7.8.14 CDP-ribitol ribitolphosphotransferase (12 March 2017)
EC 2.7.8.45 teichoic acid glycerol-phosphate transferase (12 March 2017)
EC 2.7.8.46 teichoic acid ribitol-phosphate primase (12 March 2017)
EC 2.7.8.47 teichoic acid ribitol-phosphate polymerase (12 March 2017)
*EC 2.8.1.4 tRNA uracil 4-sulfurtransferase (7 June 2017)
EC 2.8.1.15 tRNA-5-methyluridine54 2-sulfurtransferase (7 June 2017)
*EC 2.8.2.24 aromatic desulfoglucosinolate sulfotransferase (13 October 2017)
EC 2.8.2.38 aliphatic desulfoglucosinolate sulfotransferase (13 October 2017)
EC 2.8.2.39 hydroxyjasmonate sulfotransferase (13 October 2017)
EC 3.1.3.105 N-acetyl-D-muramate 6-phosphate phosphatase (13 October 2017)
EC 3.1.4.58 RNA 2',3'-cyclic 3'-phosphodiesterase (13 October 2017)
EC 3.1.7.7 transferred now EC 4.2.3.194 (13 October 2017)
EC 3.1.7.12 (+)-kolavelool synthase (13 October 2017)
EC 3.1.11.7 adenosine-5'-diphospho-5'-[DNA] diphosphatase (12 March 2017)
EC 3.1.11.8 guaosine-5'-diphospho-5'-[DNA] diphosphatase (12 March 2017)
EC 3.1.12.2 DNA-3'-diphospho-5'-guanosine diphosphatase (12 March 2017)
*EC 3.2.1.14 chitinase (12 March 2017)
*EC 3.2.1.130 glycoprotein endo-α-1,2-mannosidase (13 October 2017)
EC 3.2.1.200 exo-chitinase (non-reducing end) (12 March 2017)
EC 3.2.1.201 exo-chitinase (reducing end) (12 March 2017)
EC 3.2.1.202 endo-chitodextinase (12 March 2017)
EC 3.2.1.203 carboxymethylcellulase (7 June 2017)
EC 3.2.1.204 1,3-α-isomaltosidase (13 October 2017)
EC 3.2.1.205 isomaltose glucohydrolase (13 October 2017)
EC 3.2.1.206 oleuropein β-glucosidase (15 December 2017)
*EC 3.3.2.9 microsomal epoxide hydrolase (15 December 2017)
EC 3.4.19.16 glucosinolate γ-glutamyl hydrolase (13 October 2017)
EC 3.5.1.120 transferred, now EC 3.5.99.11 (7 June 2017)
EC 3.5.1.125 N2-acetyl-L-2,4-diaminobutanoate deacetylase (12 March 2017)
EC 3.5.1.126 oxamate amidohydrolase (12 March 2017)
EC 3.5.1.127 jasmonoyl-L-amino acid hydrolase (12 March 2017)
EC 3.5.4.44 ectoine hydrolase (12 March 2017)
EC 3.5.4.45 melamine deaminase (12 March 2017)
EC 3.5.4.46 cAMP deaminase (12 March 2017)
EC 3.5.99.11 2-aminomuconate deaminase (2-hydroxymuconate-forming) (7 June 2017)
EC 3.13.1.5 carbon disulfide hydrolase (7 June 2017)
EC 3.13.1.6 [CysO sulfur-carrier protein]-S-L-cysteine hydrolase (13 October 2017)
EC 4.1.1.104 3-dehydro-4-phosphotetronate decarboxylase (7 June 2017)
EC 4.1.1.105 L-tryptophan decarboxylase (15 December 2017)
EC 4.1.1.106 fatty acid photodecarboxylase (15 December 2017)
EC 4.1.1.107 3,4-dihydroxyphenylacetaldehyde synthase (15 December 2017)
EC 4.1.1.108 4-hydroxyphenylacetaldehyde synthase (15 December 2017)
EC 4.1.1.109 phenylacetaldehyde synthase (15 December 2017)
EC 4.1.2.59 dihydroneopterin phosphate aldolase (7 June 2017)
EC 4.1.2.60 dihydroneopterin triphosphate aldolase (7 June 2017)
EC 4.1.99.23 5-hydroxybenzimidazole synthase (15 December 2017)
*EC 4.2.1.108 ectoine synthase (12 March 2017)
EC 4.2.1.171 cis-L-3-hydroxyproline dehydratase (12 March 2017)
EC 4.2.1.172 trans-4-hydroxy-L-proline dehydratase (13 October 2017)
EC 4.2.1.173 ent-8α-hydroxylabd-13-en-15-yl diphosphate synthase (13 October 2017)
EC 4.2.1.174 peregrinol diphosphate synthase (13 October 2017)
*EC 4.2.3.141 sclareol synthase (15 December 2017)
EC 4.2.3.157 (+)-isoafricanol synthase (13 October 2017)
EC 4.2.3.158 (–)-spiroviolene synthase (13 October 2017)
EC 4.2.3.159 tsukubadiene synthase (13 October 2017)
EC 4.2.3.160 (2S,3R,6S,9S)-(–)-protoillud-7-ene synthase (13 October 2017)
EC 4.2.3.161 (3S)-(+)-asterisca-2(9),6-diene synthase (13 October 2017)
EC 4.2.3.162 (–)-α-amorphene synthase (13 October 2017)
EC 4.2.3.163 (+)-corvol ether B synthase (13 October 2017)
EC 4.2.3.164 (+)-eremophilene synthase (13 October 2017)
EC 4.2.3.165 (1R,4R,5S)-(–)-guaia-6,10(14)-diene synthase (13 October 2017)
EC 4.2.3.166 (+)-(1E,4E,6S,7R)-germacra-1(10),4-dien-6-ol synthase (13 October 2017)
EC 4.2.3.167 dolabella-3,7-dien-18-ol synthase (13 October 2017)
EC 4.2.3.168 dolathalia-3,7,11-triene synthase (13 October 2017)
EC 4.2.3.169 7-epi-α-eudesmol synthase (13 October 2017)
EC 4.2.3.170 4-epi-cubebol synthase (13 October 2017)
EC 4.2.3.171 (+)-corvol ether A synthase (13 October 2017)
EC 4.2.3.172 10-epi-juneol synthase (13 October 2017)
EC 4.2.3.173
EC 4.2.3.174 (2E,6E)-hedycaryol synthase (13 October 2017)
EC 4.2.3.175 10-epi-cubebol synthase (13 October 2017)
EC 4.2.3.176 sesterfisherol synthase (13 October 2017)
EC 4.2.3.177 β-thujene synthase (13 October 2017)
EC 4.2.3.178 stellata-2,6,19-triene synthase (13 October 2017)
EC 4.2.3.179 guaia-4,6-diene synthase (13 October 2017)
EC 4.2.3.180 pseudolaratriene synthase (13 October 2017)
EC 4.2.3.181 selina-4(15),7(11)-diene synthase (13 October 2017)
EC 4.2.3.182 pristinol synthase (13 October 2017)
EC 4.2.3.183 nezukol synthase (13 October 2017)
EC 4.2.3.184 5-hydroxy-α-gurjunene synthase (13 October 2017)
EC 4.2.3.185 ent-atiserene synthase (13 October 2017)
EC 4.2.3.186 ent-13-epi-manoyl oxide synthase (13 October 2017)
EC 4.2.3.187 (2Z,6E)-hedycaryol synthase (13 October 2017)
EC 4.2.3.188 β-geranylfarnesene synthase (13 October 2017)
EC 4.2.3.189 9,13-epoxylabda-14-ene synthase (13 October 2017)
EC 4.2.3.190 manoyl oxide synthase (13 October 2017)
EC 4.2.3.191 cycloaraneosene synthase (13 October 2017)
EC 4.2.3.192 labda-7,13(16),14-triene synthase (13 October 2017)
EC 4.2.3.193 (12E)-labda-8(17),12,14-triene synthase (13 October 2017)
EC 4.2.3.194 (–)-drimenol synthase (13 October 2017)
EC 4.2.3.195 rhizathalene A synthase (15 December 2017)
EC 4.3.2.7 glutathione-specific γ-glutamylcyclotransferase (13 October 2017)
EC 4.3.2.8 γ-glutamylamine cyclotransferase (13 October 2017)
EC 4.3.2.9 γ-glutamylcyclotransferase (13 October 2017)
EC 4.4.1.27 transferred, now EC 3.13.1.5 (7 June 2017)
EC 4.4.1.36 hercynylcysteine S-oxide lyase (13 October 2017)
EC 4.4.1.35 L-cystine β-lyase (12 March 2017)
EC 4.99.1.10 magnesium dechelatase (7 June 2017)
EC 4.99.1.11 sirohydrochlorin nickelchelatase (7 June 2017)
EC 4.99.1.12 pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel chelatase (15 December 2017)
EC 5.1.1.22 4-hydroxyproline betaine 2-epimerase (12 March 2017)
EC 5.1.2.7 tagaturonate epimerase (12 March 2017)
EC 5.1.3.40 D-tagatose 6-phosphate 4-epimerase (12 March 2017)
EC 5.1.3.41 fructoselysine 3-epimerase (7 June 2017)
EC 5.3.1.35 2-dehydrotetronate isomerase (7 June 2017)
EC 5.3.3.20 transferred now EC 5.4.99.64 (12 March 2017)
*EC 5.4.3.3 lysine 5,6-aminomutase (7 June 2017)
EC 5.4.3.4 transferred, now included in EC 5.4.3.3 (7 June 2017)
EC 5.4.4.8 linalool isomerase (13 October 2017)
EC 5.4.99.64 2-hydroxyisobutanoyl-CoA mutase (12 March 2017)
EC 5.4.99.65 pre-α-onocerin synthase (13 October 2017)
EC 5.4.99.66 α-onocerin synthase (13 October 2017)
EC 5.5.1.28 (–)-kolavenyl diphosphate synthase (13 October 2017)
EC 5.5.1.29 (+)-kolavenyl diphosphate synthase (13 October 2017)
EC 5.5.1.30 labda-7,13-dienyl diphosphate synthase (13 October 2017)
EC 6.1.3 Cyclo-ligases (13 October 2017)
EC 6.1.3.1 olefin β-lactone synthetase (13 October 2017)
EC 6.2.1.48 carnitine-CoA ligase (12 March 2017)
EC 6.2.1.49 long-chain fatty acid adenylyltransferase FadD28 (7 June 2017)
EC 6.2.1.50 4-hydroxybenzoate adenylyltransferase FadD22 (13 October 2017)
EC 6.2.1.51 4-hydroxyphenylalkanoate adenylyltransferase FadD29 (15 December 2017)
EC 6.2.1.52 L-firefly luciferin—CoA ligase (15 December 2017)
*EC 6.3.2.5 phosphopantothenate—cysteine ligase (CTP) (7 June 2017)
EC 6.3.2.50 tenuazonic acid synthetase (7 June 2017)
EC 6.3.2.51 phosphopantothenate—cysteine ligase (ATP) (7 June 2017)
EC 6.3.3.7 Ni-sirohydrochlorin a,c-diamide reductive cyclase (7 June 2017)
EC 6.3.5.12 Ni-sirohydrochlorin a,c-diamide synthase (7 June 2017)
EC 6.4.1.9 coenzyme F430 synthetase (7 June 2017)
EC 6.5.1.8 3'-phosphate/5'-hydroxy nucleic acid ligase (12 March 2017)