Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB)

Enzyme Nomenclature

Supplement 6

Three documents prepared during 1999 with additions and amendments to Enzyme Nomenclature were approved in May 2000 after public review:

New peptidases (EC 3.4)
Other new enzymes
ATPases and GTPases (all in EC 3.6)

Two more documents with additions and amendments to Enzyme Nomenclature were approved in October 2000 after public review:

New peptidases (EC 3.4)
Other new enzymes

One more document with additions and amendments to Enzyme Nomenclature were approved in December 2000 after public review:

New enzymes

An asterisk before 'EC' indicates that this is an amendment to an existing enzyme rather than a new enzyme entry.

Contents

EC 1.1.1.255 mannitol dehydrogenase
EC 1.1.1.256 fluoren-9-ol dehydrogenase
EC 1.1.1.257 4-(hydroxymethyl)benzenesulfonate dehydrogenase
EC 1.1.1.258 6-hydroxyhexanoate dehydrogenase
EC 1.1.1.259 3-hydroxypimeloyl-CoA dehydrogenase
EC 1.1.1.260 sulcatone reductase
EC 1.1.1.261 glycerol-1-phosphate dehydrogenase [NAD(P)]
EC 1.1.1.262 4-hydroxythreonine-4-phosphate dehydrogenase
EC 1.1.1.263 1,5-anhydro-D-fructose reductase
EC 1.1.1.264 L-idonate 5-dehydrogenase
EC 1.1.1.265 3-methylbutanal reductase
EC 1.2.1.60 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
EC 1.2.1.61 4-hydroxymuconic semialdehyde dehydrogenase
EC 1.2.1.62 4-formylbenzenesulfonate dehydrogenase
EC 1.2.1.63 6-oxohexanoate dehydrogenase
EC 1.2.1.64 4-hydroxybenzaldehyde dehydrogenase
EC 1.2.1.65 salicylaldehyde dehydrogenase
EC 1.2.1.66 mycothiol-dependent formaldehyde dehydrogenase
EC 1.2.1.67 vanillin dehydrogenase
EC 1.2.1.68 coniferyl-aldehyde dehydrogenase
EC 1.2.3.12 vanillate demethylase
EC 1.2.3.13 4-hydroxyphenylpyruvate oxidase
EC 1.3.1.56 cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
EC 1.3.1.57 phloroglucinol reductase
EC 1.3.1.58 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase
EC 1.3.1.59 1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate dehydrogenase
EC 1.3.1.60 dibenzothiophene dihydrodiol dehydrogenase
EC 1.3.1.61 terephthalate 1,2-cis-dihydrodiol dehydrogenase
EC 1.3.1.62 pimeloyl-CoA dehydrogenase
EC 1.3.1.63 2,4-dichlorobenzoyl-CoA reductase
EC 1.3.1.64 phthalate 4,5-cis-dihydrodiol dehydrogenase
EC 1.3.1.65 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase
EC 1.3.1.66 cis-dihydroethylcatechol dehydrogenase
EC 1.3.1.67 cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase
EC 1.3.1.68 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase
EC 1.3.99.20 4-hydroxybenzoyl-CoA reductase
EC 1.4.3.17 tryptophan α,β-oxidase
EC 1.4.3.18 not approved
EC 1.5.99.11 coenzyme F₄₂₀-dependent N⁵,N¹⁰-methenyltetrahydromethanopterin reductase
EC 1.6.5.6 p-benzoquinone reductase (NADPH)
EC 1.6.5.7 2-hydroxy-1,4-benzoquinone reductase
*EC 1.6.99.3 NADH₂ dehydrogenase
EC 1.8.4.8 phosphoadenylyl-sulfate reductase (thioredoxin)
EC 1.8.4.9 adenylyl-sulfate reductase (glutathione) EC 1.8.99.4 now EC 1.8.4.8
*EC 1.9.3.1 cytochrome-c oxidase
*EC 1.10.2.2 ubiquinol-cytochrome-c reductase
EC 1.13.11.44 linoleate diol synthase
EC 1.13.11.45 linoleate 11-lipoxygenase
EC 1.13.12.12 apo-β-carotenoid-14',13'-dioxygenase
*EC 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
EC 1.14.11.17 taurine dioxygenase
EC 1.14.11.18 phytanoyl-CoA dioxygenase
EC 1.14.12.17 nitric oxide dioxygenase
EC 1.14.13.67 quinine 3-monooxygenase
EC 1.14.13.68 4-hydroxyphenylacetaldehyde oxime monooxygenase
EC 1.14.14.4 choline monooxygenase
EC 1.14.19 With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
EC 1.14.19.1 stearoyl-CoA 9-desaturase
EC 1.14.19.2 acyl-[acyl-carrier-protein] desaturase
EC 1.14.19.3 linoleoyl-CoA desaturase
EC 1.14.99.5 stearoyl-CoA 9-desaturase
EC 1.14.99.5 now EC 1.14.19.1
EC 1.14.99.6 acyl-[acyl-carrier-protein] 9-desaturase
EC 1.14.99.6 now EC 1.14.19.2
EC 1.14.99.25 now EC 1.14.19.3
EC 1.14.99.31 myristoyl-CoA 11-(E) desaturase
EC 1.14.99.32 myristoyl-CoA 11-(Z) desaturase
EC 1.14.99.33 δ¹²-fatty acid dehydrogenase
EC 1.14.99.34 monoprenyl isoflavone epoxidase
EC 1.14.99.35 thiophene-2-carbonyl-CoA monooxygenase
EC 1.97.1.5 arsenate reductase (glutaredoxin)
EC 1.97.1.6 arsenate reductase (donor)
EC 1.97.1.7 methylarsonate reductase
*EC 2.1.1.86 tetrahydromethanopterin S-methyltransferase
EC 2.1.1.136 chlorophenol O-methyltransferase
EC 2.1.1.137 arsenite methyltransferase
EC 2.1.1.138 methylarsonite methyltransferase
EC 2.1.1.139 3'-demethylstaurosporine O-methyltransferase
*EC 2.1.2.2 phosphoribosylglycinamide formyltransferase
*EC 2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
*EC 2.1.2.4 glycine formimidoyltransferase
*EC 2.1.2.5 glutamate formimidoyltransferase
EC 2.3.1.154 propionyl-CoA C²-trimethyltridecanoyltransferase
EC 2.3.1.155 acetyl-CoA C-myristoyltransferase
EC 2.3.1.156 phloroisovalerophenone synthase
EC 2.4.1.209 cis-p-coumarate glucosyltransferase
EC 2.4.1.210 limonoid glucosyltransferase
*EC 2.6.1.16 glutamine-fructose-6-phosphate transaminase (isomerizing)
EC 2.6.1.76 diaminobutyrate-2-oxoglutarate transaminase
*EC 2.7.1.69 protein-N^π-phosphohistidine-sugar phosphotransferase
EC 3.1.1.73 feruloyl esterase
EC 3.1.1.74 cutinase
EC 3.1.2.24 2-(2-hydroxyphenyl)benzenesulfinate hydrolase
*EC 3.1.14 Exoribonucleases Producing 3'-Phosphomonoesters
*EC 3.1.16 Exonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 3'-Phosphomonoesters
*EC 3.1.31 Endoribonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 3'-Phosphomonoesters
*EC 3.2.1.10 oligosaccharide α1,6- glucosidase
*EC 3.2.1.33 amylo-α-1,6-glucosidase
*EC 3.2.1.41 pullulanase
*EC 3.2.1.68 isoamylase
EC 3.2.1.142 limit dextrinase
EC 3.2.1.143 poly(ADP-ribose) glycohydrolase
EC 3.2.1.144 3-deoxyoctulosonase
*EC 3.2.2.15 DNA-deoxyinosine glycosylase
*EC 3.2.2.20 DNA-3-methyladenine glycosylase I
*EC 3.2.2.21 DNA-3-methyladenine glycosylase II
*EC 3.2.2.22 rRNA N-glycosylase
*EC 3.2.2.23 DNA-formamidopyrimidine glycosylase
EC 3.4.11.21 aspartyl aminopeptidase
EC 3.4.13.8 now EC 3.4.13.18
*EC 3.4.13.18 cytosol nonspecific dipeptidase
*EC 3.4.14.9 tripeptidyl-peptidase I
*EC 3.4.17.10 carboxypeptidase E
*EC 3.4.17.21 glutamate carboxypeptidase II
EC 3.4.19.8 now EC 3.4.17.21
*EC 3.4.18.1 cathepsin X
EC 3.4.19.12 ubiquitinyl hydrolase 1
EC 3.4.21.97 assemblin
EC 3.4.21.98 hepacivirin
*EC 3.4.22.2 papain
*EC 3.4.22.34 legumain
EC 3.4.22.39 adenain
EC 3.4.22.40 bleomycin hydrolase
EC 3.4.22.41 cathepsin F
EC 3.4.22.42 cathepsin O
EC 3.4.22.43 cathepsin V
EC 3.4.22.44 nuclear-inclusion-a endopeptidase
*EC 3.4.23.16 HIV-1 retropepsin
EC 3.4.23.41 yapsin 1
EC 3.4.23.42 thermopsin
*EC 3.4.24.38 gametolysin
EC 3.4.24.76 flavastacin
EC 3.4.25 Threonine Endopeptidases
EC 3.4.25.1 proteasome endopeptidase complex
EC 3.4.99.43 now EC 3.4.23.42
EC 3.4.99.46 now EC 3.4.25.1
EC 3.5.1.84 biuret amidohydrolase
EC 3.5.1.85 (S)-N-acetyl-1-phenylethylamine hydrolase
EC 3.5.1.86 mandelamide amidase
EC 3.5.2.15 cyanuric acid amidohydrolase
*EC 3.5.3.5 formimidoylaspartate deiminase
*EC 3.5.3.8 formimidoylglutamase
*EC 3.5.3.13 formimidoylglutamate deiminase
*EC 3.5.4.10 IMP cyclohydrolase
*EC 3.5.4.19 phosphoribosyl-AMP cyclohydrolase
EC 3.5.5.8 thiocyanate hydrolase
EC 3.5.99.3 hydroxydechloroatrazine ethylaminohydrolase
EC 3.5.99.4 N-isopropylammelide isopropylaminohydrolase
EC 3.5.99.5 2-aminomuconate deaminase
EC 3.5.99.6 glucosamine-6-phosphate deaminase
EC 3.6.1.32 now EC 3.6.4.1
EC 3.6.1.33 now EC 3.6.4.2
EC 3.6.1.34 now EC 3.6.3.14
EC 3.6.1.35 now EC 3.6.3.6
EC 3.6.1.36 now EC 3.6.3.10
EC 3.6.1.37 now EC 3.6.3.9
EC 3.6.1.38 now EC 3.6.3.8
*EC 3.6.1.1 inorganic diphosphatase
*EC 3.6.1.5 apyrase
EC 3.6.1.46 heterotrimeric G-protein GTPase
EC 3.6.1.47 small monomeric GTPase
EC 3.6.1.48 protein-synthesizing GTPase
EC 3.6.1.49 signal-recognition-particle GTPase
EC 3.6.1.50 dynamin GTPase
EC 3.6.1.51 tubulin GTPase
EC 3.6.3 Acting on acid anhydrides; catalysing transmembrane movement of substances.
EC 3.6.3.1 Mg²⁺-ATPase
EC 3.6.3.2 Mg²⁺-importing ATPase
EC 3.6.3.3 Cd²⁺-exporting ATPase
EC 3.6.3.4 Cu²⁺-exporting ATPase
EC 3.6.3.5 Zn²⁺-exporting ATPase
EC 3.6.3.6 H⁺-exporting ATPase
EC 3.6.3.7 Na⁺-exporting ATPase
EC 3.6.3.8 Ca²⁺-transporting ATPase
EC 3.6.3.9 Na⁺/K⁺-exchanging ATPase
EC 3.6.3.10 H⁺/K⁺-exchanging ATPase
EC 3.6.3.11 Cl^--transporting ATPase
EC 3.6.3.12 K⁺-transporting ATPase
EC 3.6.3.13 aminophospholipid-transporting ATPase
EC 3.6.3.14 H⁺-transporting two-sector ATPase
EC 3.6.3.15 Na⁺-transporting two-sector ATPase
EC 3.6.3.16 arsenite-transporting ATPase
EC 3.6.3.17 monosaccharide-transporting ATPase
EC 3.6.3.18 oligosaccharide-transporting ATPase
EC 3.6.3.19 maltose-transporting ATPase
EC 3.6.3.20 glycerol-3-phosphate-transporting ATPase
EC 3.6.3.21 polar-amino-acid-transporting ATPase
EC 3.6.3.22 nonpolar-amino-acid-transporting ATPase
EC 3.6.3.23 oligopeptide-transporting ATPase
EC 3.6.3.24 nickel-transporting ATPase
EC 3.6.3.25 sulfate-transporting ATPase
EC 3.6.3.26 nitrate-transporting ATPase
EC 3.6.3.27 phosphate-transporting ATPase
EC 3.6.3.28 phosphonate-transporting ATPase
EC 3.6.3.29 molybdate-transporting ATPase
EC 3.6.3.30 Fe³⁺-transporting ATPase
EC 3.6.3.31 polyamine-transporting ATPase
EC 3.6.3.32 quaternary-amine-transporting ATPase
EC 3.6.3.33 vitamin B₁₂-transporting ATPase
EC 3.6.3.34 iron-chelate-transporting ATPase
EC 3.6.3.35 manganese-transporting ATPase
EC 3.6.3.36 taurine-transporting ATPase
EC 3.6.3.37 guanine-transporting ATPase
EC 3.6.3.38 capsular-polysaccharide-transporting ATPase
EC 3.6.3.39 lipopolysaccharide-transporting ATPase
EC 3.6.3.40 teichoic-acid-transporting ATPase
EC 3.6.3.41 heme-transporting ATPase
EC 3.6.3.42 β-glucan-transporting ATPase
EC 3.6.3.43 peptide-transporting ATPase
EC 3.6.3.44 xenobiotic-transporting ATPase
EC 3.6.3.45 steroid-transporting ATPase
EC 3.6.3.46 cadmium-transporting ATPase
EC 3.6.3.47 fatty-acyl-CoA-transporting ATPase
EC 3.6.3.48 α-factor-transporting ATPase
EC 3.6.3.49 channel-conductance-controlling ATPase
EC 3.6.3.50 protein-secreting ATPase
EC 3.6.3.51 mitochondrial protein-transporting ATPase
EC 3.6.3.52 chloroplast protein-transporting ATPase
EC 3.6.3.53 Ag⁺-exporting ATPase
EC 3.6.4 Acting on acid anhydrides; involved in cellular and subcellular movement.
EC 3.6.4.1 myosin ATPase
EC 3.6.4.2 dynein ATPase
EC 3.6.4.3 microtubule-severing ATPase
EC 3.6.4.4 plus-end-directed kinesin ATPase
EC 3.6.4.5 minus-end-directed kinesin ATPase
EC 3.6.4.6 vesicle-fusing ATPase
EC 3.6.4.7 peroxisome-assembly ATPase
EC 3.6.4.8 proteasome ATPase
EC 3.6.4.9 chaperonin ATPase
EC 3.6.4.10 non-chaperonin molecular chaperone ATPase
EC 3.6.4.11 nucleoplasmin ATPase
EC 3.8.1.8 atrazine chlorohydrolase
*EC 4.1.1.3 oxaloacetate decarboxylase
*EC 4.1.1.21 phosphoribosylaminoimidazole carboxylase
EC 4.1.1.78 acetylenedicarboxylate decarboxylase
EC 4.1.2.41 vanillin synthase
EC 4.1.99.6 now EC 4.2.3.6
EC 4.1.99.7 now EC 4.2.3.9
EC 4.1.99.8 pinene synthase
EC 4.1.99.8 now EC 4.2.3.14
EC 4.1.99.9 myrcene synthase
EC 4.1.99.9 now EC 4.2.3.15
EC 4.1.99.10 (-)-(4S)-limonene synthase
EC 4.1.99.10 now EC 4.2.3.16
EC 4.1.99.11 benzylsuccinate synthase
*EC 4.2.1.71 acetylenecarboxylate hydratase
EC 4.2.1.72 now EC 4.1.1.78
EC 4.2.1.100 cyclohexa-1,5-dienecarbonyl-CoA hydratase
EC 4.2.1.101 trans-feruloyl-CoA hydratase
EC 4.2.2.14 glucuronan lyase
EC 4.2.3 Acting on phosphates
EC 4.2.3.1 threonine synthase
EC 4.2.3.2 ethanolamine-phosphate phospho-lyase
EC 4.2.3.3 methylglyoxal synthase
EC 4.2.3.4 3-dehydroquinate synthase
EC 4.2.3.5 chorismate synthase
EC 4.2.3.6 trichodiene synthase
EC 4.2.3.7 pentalenene synthase
EC 4.2.3.8 casbene synthase
EC 4.2.3.9 aristolochene synthase
EC 4.2.3.10 (-)-endo-fenchol synthase
EC 4.2.3.11 sabinene-hydrate synthase
EC 4.2.3.12 6-pyruvoyltetrahydropterin synthase
EC 4.2.3.13 (+)-δ-cadinene synthase
EC 4.2.3.14 pinene synthase
EC 4.2.3.15 myrcene synthase
EC 4.2.3.16 (-)-(4S)-limonene synthase
EC 4.2.99.2 now EC 4.2.3.1
EC 4.2.99.7 now EC 4.2.3.2
EC 4.2.99.11 now EC 4.2.3.3
*EC 4.3.1.4 formimidoyltetrahydrofolate cyclodeaminase
*EC 4.3.2.2 adenylosuccinate lyase
EC 4.3.3.3 deacetylisoipecoside synthase
EC 4.3.3.4 deacetylipecoside synthase
EC 4.4.1.18 prenylcysteine lyase
EC 4.6.1.3 now EC 4.2.3.4
EC 4.6.1.4 now EC 4.2.3.5
EC 4.6.1.5 now EC 4.2.3.7
EC 4.6.1.7 now EC 4.2.3.8
EC 4.6.1.8 now EC 4.2.3.10
EC 4.6.1.9 now EC 4.2.3.11
EC 4.6.1.10 now EC 4.2.3.12
EC 4.6.1.11 now EC 4.2.3.13
EC 5.3.1.10 now EC 3.5.99.6
*EC 5.3.1.16 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase
EC 6.2.1.34 trans-feruloyl-CoA synthase
*EC 6.3.2.6 phosphoribosylaminoimidazolesuccinocarboxamide synthase
*EC 6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
*EC 6.3.4.13 phosphoribosylamine-glycine ligase
*EC 6.3.5.3 phosphoribosylformylglycinamidine synthase

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