| Deletions | ||
| 1.A.30.1 | H+- or Na+-translocating bacterial flagellar motor | Mot |
| 1.A.30.2 | TonB-ExbB-ExbD/TolA-TolQ-TolR of energizers for outer-membrane receptor (OMR)-mediated active transport | Exb |
| 1.C.53 | Bacteriocin AS-48 cyclic polypeptide | Bacteriocin AS-48 |
| 1.D.11 | ||
| Change | ||
| 1.A.30 | H+- or Na+-translocating MotAB flagellar motor | |
| Add | ||
| 1.A.37 | CD20 Ca2+ channel | CD20 |
| 1.A.38 | Poliovirus 2B viroporin | 2B Viroporin |
| 1.A.39 | Type C influenza virus CM2 channel | CM2-C |
| 1.A.40 | Human immunodeficiency virus type 1 channel | Vpu-C |
| 1.B.35 | Oligogalacturonate-specific pori | KdgM |
| 1.B.36 | Borrelia porin p13 | BP-p13 |
| 1.B.37 | Leptospira porin OmpL1 | LP-OmpL1 |
| 1.B.38 | Treponema porin major surface protein | TP-MSP |
| 1.C.59 | Clostridium perfringens enterotoxin | CPE |
| 1.C.60 | Two-component Enterococcus faecalis cytolysin | EFC |
| 1.C.61 | Streptococcus pyogenes streptolysin S | Streptolysin S |
| 1.C.62 | Pseudopleuronectes americanus pleurocidin | Pleurocidin |
| 1.C.6 | a-Latrotoxin | Latrotoxin |
| 1.C.64 | Fst toxin | Fst |
| 1.C.65 | Plant host cell membrane pore-forming protein of type III protein secretion system | HrpF |
| 1.D.12 | Beauvericin | Beauvericin |
| 1.E.20 | Pseudomonas aeruginosa Hol holin | Hol Holin |
| 1.E.21 | Listeria phage A118 holin | holin118 |
| 2.A.81 | Aspartate:alanine exchanger | AAE |
| 2.C | Ion-gradient-driven energizers | |
| 2.C.1 | TonB-ExbB-ExbD/TolA-TolQ-TolR proteins for energization of outer-membrane-receptor-mediated transport | TonB |
| 3.A.1.122 | Macrolide exporter | MacB |
| 3.A.1.123 | Peptide-4 exporter | Pep4E |
| 3.A.1.124 | Three-component peptide-5 exporter | Pep5E |
| 3.A.1.125 | Lipoprotein translocase | LPT |
| 3.A.1.126 | b-Exotoxin I exporter | b ETE |
| 3.A.15 | Outer membrane protein secreting main terminal branch | MTB |
| 4.A.7 | l-Ascorbate PTS | l-Asc |
| 5.A.3 | Prokaryotic molybdopterin-containing oxidoreductase | PMO |
| Deletions | |||||||
| 1.A.30.1 | Mot | H+; Na+ | 200-350 (MotA)200-500 (MotB) | 41 | B | 2 | MotA and MotB proteins of Escherichia coli |
| 1.A.30.2 | Exb | H+ (energy-transducing system) | 150-400+150- 350+100-200 (TonB ExbBD) 350-450+200- 300+100-200 (TolAQR) | 1+3+1 1+3+1 | B(G-) | 2 | TonB/ExbB/ExbD of Escherichia coli |
| 1.C.53 | Bacteriocin AS-48 | ions and small molecules | 70 (cyclic) (precursors: 105) | 1 | B(G+) | 0 | bacteriocin AS-48 of Enterococcus faecalis |
| 1.D.11 | PEA | mainly K+, also organic compounds | no amino acids, c. 920 Da | - | B | 1 | amphotericin B of Streptomyces nodosus |
| Change | |||||||
| 1.A.30 | Mot | H+; Na+ | 200-350 (MotA)200-500 (MotB) | 41 | B | 2 | MotA and MotB proteins of Escherichia coli |
| Add | |||||||
| 1.A.37 | CD20 | Ca2+ | 297 | 4 | E(An) | 0 | CD20 of Homo sapiens |
| 1.A.38 | 2B Viroporin | molecules smaller than 1 kDa | 97 | nonstructural tetramer | V | 0 | 2B viroporin of poliovirus |
| 1.A.39 | CM2-C | small molecules | 139 | 2 | V | 0 | CM2 of type C influenza virus |
| 1.A.40 | Vpu-C | ions (mainly univalent cations) | 81 | homopentamer | E(An) | 0 | Vpu of HIV-1 |
| 1.B.35 | KdgM | anions preferred | 236 | monomeric | B(G-) | 0 | KdgM of Erwinia chrysanthemi |
| 1.B.36 | BP-p13 | cations | c. 115 | partly a-helical | B | 0 | p13 porin of Borrelia burgdorferi |
| 1.B.37 | LP-OmpL1 | small molecules | c. 270 | trimeric | B | 0 | OmpL1 of Leptospira kirschneri |
| 1.B.38 | TP-MSP | ions | 474 | hexagonal | B | 0 | Msp of Treponema denticola |
| 1.C.59 | CPE | small molecules | 309 | forms complexes | B | 1 | enterotoxin of Clostridium perfringens |
| 1.C.60 | EFS | small molecules | 68+63 | forms complexes | B(G+) | 0 | CylL of Enterococcus faecalis |
| 1.C.61 | Streptolysin S | small molecules | 53 | 1 | B | 0 | SagA of Streptococcus pyogenes |
| 1.C.62 | Pleurocidin | small molecules | 25 | toroidal pore | E(fish) | 0 | pleurocidin of Pseudopleuronectes americanus |
| 1.C.63 | Latrotoxin | cations | 4 ? c. 1050 | tetrameric pore | E(spiders) | 0 | a-latrotoxin of Latrodectus mactans |
| 1.C.64 | Fst | small molecules (selective) | 33 | ? | B | 0 | Fst of Enterococcus faecalis plasmid pAD1 |
| 1.C.65 | HrpF | proteins | 806 | 3(?) part of translocon | B | 0 | HrpF of Xanthomonas campestris |
| 1.D.12 | Beauvericin | cations (mainly Na+, K+, Ca2+) | cyclic hexadepsipeptide of d-a-hydroxyisovaleryl and N-methylphenylalanyl residues | B | 0 | beauvericin of Beauveria bassiana | |
| 1.E.20 | Hol | Holin autolysin | 117 | 1-2 | B(G-) | 1 | Hol of Pseudomonas aeruginosa PAO1 |
| 1.E.21 | hol118 | small molecules, autolysin | 93 | 3 | Bp | 0 | hol118 of Listeria monocytogenes phage A118 |
| 2.A.81 | AAE | aspartate:alanine | 543 | 11-13 | B(G-) | 1 | AspT of Tetragenococcus halophila |
| 2.C. | Ion-gradient-driven transporters | ||||||
| These proteins use proton-motive or sodium-motive force to energize the movement of substances through porins or other bacterial outer membrane receptors against concentration gradients. | |||||||
| 2.C.1 | TonB | various molecules (colicin, vitamin B12, siderophores and others) | 239+244+141/ mainly 412+230+142 | 3 | B(G-) | 1 | TonB/ExbBD system of Escherichia coli |
| 3.A.15 | MTB | folded proteins | >14 proteins | various | B | 1 | pullulanase secretion system of Klebsiella pneumoniae |
| 4.A.7 | L-Asc | l-ascorbate | 3 | proteins (SgaTBA with 12 TMS) | B | 1 | l-ascorbate IIC-IIB-IIA complex of Escherichia coli |
| 5.A.3 | PMO | 2 e- | 2_1247 2_512 4_225 | 5 (plus nonintegral proteins) | B, A | 1 | NarGHI of Escherichia coli |