IUBMB Enzyme Nomenclature


Accepted name: 4-hydroxybutyrate dehydrogenase

Reaction: 4-hydroxybutanoate + NAD+ = succinate semialdehyde + NADH + H+

For diagram of reaction click here.

Other name(s): γ-hydroxybutyrate dehydrogenase

Systematic name: 4-hydroxybutanoate:NAD+ oxidoreductase

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9028-60-8


1. Nirenberg, M.W. and Jakoby, W.B. Enzymatic utilization of γ-hydroxybutyric acid J. Biol. Chem. 235 (1960) 954-960.

[EC created 1965]

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