IUBMB Enzyme Nomenclature


Accepted name: alcohol dehydrogenase [NAD(P)+]

Reaction: an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+

For diagram of reaction click here.

Other name(s): retinal reductase (ambiguous); aldehyde reductase (NADPH/NADH); alcohol dehydrogenase [NAD(P)]

Systematic name: alcohol:NAD(P)+ oxidoreductase

Comments: Reduces aliphatic aldehydes of carbon chain length from 2 to 14, with greatest activity on C4, C6 and C8 aldehydes; also reduces retinal to retinol.

Links to other databases: BRENDA, EAWAG-BBD, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37250-10-5


1. Fidge, N.H. and Goodman, D.S. The enzymatic reduction of retinal to retinol in rat intestine. J. Biol. Chem. 243 (1968) 4372-4379. [PMID: 4300551]

[EC created 1972]

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