IUBMB Enzyme Nomenclature


Accepted name: resorcinol 4-hydroxylase (NADH)

Reaction: resorcinol + NADH + H+ + O2 = hydroxyquinol + NAD+ + H2O

Glossary: resorcinol = 1,3-dihydroxybenzene
hydroxyquinol = 1,2,4-trihydroxybenzene

Other name(s): tsdB (gene name)

Systematic name: resorcinol,NADH:oxygen oxidoreductase (4-hydroxylating)

Comments: The enzyme, characterized from the bacterium Rhodococcus jostii RHA1, is a single-component hydroxylase. The enzyme has no activity with NADPH. cf. EC, resorcinol 4-hydroxylase (NADPH), and EC, resorcinol 4-hydroxylase (FADH2).

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Kasai, D., Araki, N., Motoi, K., Yoshikawa, S., Iino, T., Imai, S., Masai, E. and Fukuda, M. γ-Resorcylate catabolic-pathway genes in the soil actinomycete Rhodococcus jostii RHA1. Appl. Environ. Microbiol. 81 (2015) 7656-7665. [PMID: 26319878]

[EC created 2016]

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