IUBMB Enzyme Nomenclature

EC 1.2.1.36

Accepted name: retinal dehydrogenase

Reaction: retinal + NAD+ + H2O = retinoate + NADH + 2 H+

For diagram of reaction click here.

Other name(s): cytosolic retinal dehydrogenase

Systematic name: retinal:NAD+ oxidoreductase

Comments: A metalloflavoprotein (FAD). Acts on both the 11-trans- and 13-cis-forms of retinal.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37250-99-0

References:

1. Moffa, D.J., Lotspeich, F.J. and Krause, R.F. Preparation and properties of retinal-oxidizing enzyme from rat intestinal mucosa. J. Biol. Chem. 245 (1970) 439-447. [PMID: 4312676]

[EC 1.2.1.36 created 1972]


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