Reaction: retinal + NAD+ + H2O = retinoate + NADH + 2 H+
For diagram of reaction click here.
Other name(s): cytosolic retinal dehydrogenase
Systematic name: retinal:NAD+ oxidoreductase
Comments: A metalloflavoprotein (FAD). Acts on both the 11-trans- and 13-cis-forms of retinal.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37250-99-0
References:
1. Moffa, D.J., Lotspeich, F.J. and Krause, R.F. Preparation and properties of retinal-oxidizing enzyme from rat intestinal mucosa. J. Biol. Chem. 245 (1970) 439-447. [PMID: 4312676]