Reaction: 5,10-methylenetetrahydrofolate + NAD+ = 5,10-methenyltetrahydrofolate + NADH + H+
For diagram of reaction click here.
Other name(s): methylenetetrahydrofolate dehydrogenase (NAD)
Systematic name: 5,10-methylenetetrahydrofolate:NAD+ oxidoreductase
Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 82062-90-6
References:
1. Moore, M.R., O'Brien, W.E. and Ljungdahl, L.G. Purification and characterization of nicotinamide adenine dinucleotide-dependent methylenetetrahydrofolate dehydrogenase from Clostridium formicoaceticum. J. Biol. Chem. 249 (1974) 5250-5253. [PMID: 4153026]