Folate Cofactors

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For summary of C1 metabolism click here.

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folate biosynthesis from pteroate.
formylation, hydroxymethylation and methylation using folate.
EC 1.5.1.3 dihydrofolate reductase
EC 1.5.1.5 methylenetetrahydrofolate dehydrogenase (NADP+)
EC 1.5.1.6 formyltetrahydrofolate dehydrogenase
EC 1.5.1.15 methylenetetrahydrofolate dehydrogenase (NAD+)
EC 1.5.1.20 methylenetetrahydrofolate reductase [NAD(P)H]
EC 1.5.1.53 methylenetetrahydrofolate reductase (NADPH)
EC 1.5.1.54 methylenetetrahydrofolate reductase (NADH)
EC 1.5.7.1 methylenetetrahydrofolate reductase (ferredoxin)
EC 2.1.1.13 5-methyltetrahydrofolate-homocysteine S-methyltransferase (mechanism)
EC 2.1.1.19 trimethylsulfonium-tetrahydrofolate N-methyltransferase
EC 2.1.2.1 glycine hydroxymethyltransferase
EC 2.1.2.4 glycine formiminotransferase
EC 2.1.2.5 glutamate formiminotransferase
EC 3.5.1.10 formyltetrahydrofolate deformylase
EC 3.5.4.9 methenyltetrahydrofolate cyclohydrolase
EC 4.3.1.4 formiminotetrahydrofolate cyclodeaminase
EC 6.3.3.2 5-formyltetrahydrofolate cyclo-ligase
EC 6.3.4.3 formate-tetrahydrofolate ligase