IUBMB Enzyme Nomenclature


Accepted name: trimethylsulfonium—tetrahydrofolate N-methyltransferase

For diagram of reaction click here.

Reaction: trimethylsulfonium + tetrahydrofolate = dimethylsulfide + 5-methyltetrahydrofolate

For diagram of reaction click here.

Other name(s): trimethylsulfonium-tetrahydrofolate methyltransferase

Systematic name: trimethylsulfonium:tetrahydrofolate N-methyltransferase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37256-92-1


1. Wagner, C., Lusty, S.M., Jr., Kung, H.-F. and Rodgers, N.L. Preparation and properties of trimethylsulfonium-tetrahydrofolate methyltransferase. J. Biol. Chem. 242 (1967) 1287-1293. [PMID: 6023571]

[EC created 1972]

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