IUBMB Enzyme Nomenclature


Accepted name: formyltetrahydrofolate dehydrogenase

Reaction: 10-formyltetrahydrofolate + NADP+ + H2O = tetrahydrofolate + CO2 + NADPH + H+

For diagram of reaction click here (another example).

Other name(s): 10-formyl tetrahydrofolate:NADP oxidoreductase; 10-formyl-H2PtGlu:NADP oxidoreductase ; 10-formyl-H4folate dehydrogenase; N10-formyltetrahydrofolate dehydrogenase ; 10-formyltetrahydrofolate dehydrogenase

Systematic name: 10-formyltetrahydrofolate:NADP+ oxidoreductase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37256-25-0


1. Kutzbach, C. and Stokstad, E.L.R. Partial purification of a 10-formyl-tetrahydrofolate: NADP oxidoreductase from mammalian liver. Biochem. Biophys. Res. Commun. 30 (1968) 111-117. [PMID: 4384443]

[EC created 1972]

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