Reaction: 10-formyltetrahydrofolate + NADP+ + H2O = tetrahydrofolate + CO2 + NADPH + H+
For diagram of reaction click here (another example).
Other name(s): 10-formyl tetrahydrofolate:NADP oxidoreductase; 10-formyl-H2PtGlu:NADP oxidoreductase ; 10-formyl-H4folate dehydrogenase; N10-formyltetrahydrofolate dehydrogenase ; 10-formyltetrahydrofolate dehydrogenase
Systematic name: 10-formyltetrahydrofolate:NADP+ oxidoreductase
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37256-25-0
References:
1. Kutzbach, C. and Stokstad, E.L.R. Partial purification of a 10-formyl-tetrahydrofolate: NADP oxidoreductase from mammalian liver. Biochem. Biophys. Res. Commun. 30 (1968) 111-117. [PMID: 4384443]