IUBMB Enzyme Nomenclature


Accepted name: 5,7-dihydroxy-2-methylchromone synthase

Reaction: 5 malonyl-CoA = 5 CoA + 5,7-dihydroxy-2-methyl-4H-chromen-4-one + 5 CO2 + H2O

For diagram of reaction click here.

Other name(s): pentaketide chromone synthase

Systematic name: malonyl-CoA:malonyl-CoA malonyltransferase (5,7-dihydroxy-2-methyl-4H-chromen-4-one-forming)

Comments: A polyketide synthase from the plant Aloe arborescens (aloe).

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number:


1. Abe, I., Utsumi, Y., Oguro, S., Morita, H., Sano, Y. and Noguchi, H. A plant type III polyketide synthase that produces pentaketide chromone. J. Am. Chem. Soc. 127 (2005) 1362-1363. [PMID: 15686354]

[EC created 2013]

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