IUBMB Enzyme Nomenclature


Accepted name: cellulose synthase (UDP-forming)

Reaction: UDP-α-D-glucose + [(1→4)-β-D-glucosyl]n = UDP + [(1→4)-β-D-glucosyl]n+1

Other name(s): UDP-glucose—β-glucan glucosyltransferase; UDP-glucose-cellulose glucosyltransferase; GS-I; β-1,4-glucosyltransferase; uridine diphosphoglucose-1,4-β-glucan glucosyltransferase; β-1,4-glucan synthase; β-1,4-glucan synthetase; β-glucan synthase; 1,4-β-D-glucan synthase; 1,4-β-glucan synthase; glucan synthase; UDP-glucose-1,4-β-glucan glucosyltransferase; uridine diphosphoglucose-cellulose glucosyltransferase; UDP-glucose:1,4-β-D-glucan 4-β-D-glucosyltransferase

Systematic name: UDP-α-D-glucose:(1→4)-β-D-glucan 4-β-D-glucosyltransferase (configuration-inverting)

Comments: Involved in the synthesis of cellulose. A similar enzyme utilizes GDP-glucose [EC cellulose synthase (GDP-forming)].

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9027-19-4


1. Glaser, L. The synthesis of cellulose in cell-free extracts of Acetobacter xylinum. J. Biol. Chem. 232 (1958) 627-636. [PMID: 13549448]

[EC created 1961]

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