IUBMB Enzyme Nomenclature


Accepted name: cellulose synthase (GDP-forming)

Reaction: GDP-α-D-glucose + [(1→4)-β-D-glucosyl]n = GDP + [(1→4)-β-D-glucosyl]n+1

Other name(s): cellulose synthase (guanosine diphosphate-forming); cellulose synthetase; guanosine diphosphoglucose-1,4-β-glucan glucosyltransferase; guanosine diphosphoglucose-cellulose glucosyltransferase; GDP-glucose:1,4-β-D-glucan 4-β-D-glucosyltransferase

Systematic name: GDP-α-D-glucose:(1→4)-β-D-glucan 4-β-D-glucosyltransferase (configuration-inverting)

Comments: Involved in the synthesis of cellulose. A similar enzyme [EC, cellulose synthase (UDP-forming)] utilizes UDP-glucose.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9027-18-3


1. Chambers, J.C. and Elbein, A.D. Biosynthesis of glucans in mung bean seedlings. Formation of β-(1,4)-glucans from GDP-glucose and β-(1,3)-glucans from UDP-glucose. Arch. Biochem. Biophys. 138 (1970) 620-631. [PMID: 4317490]

2. Flowers, H.M., Batra, K.K., Kemp, J. and Hassid, W.Z. Biosynthesis of cellulose in vitro from guanosine diphosphate D-glucose with enzymic preparations from Phaseolus aureus and Lupinus albus.J. Biol. Chem. 244 (1969) 4969-4674. [PMID: 5824571]

[EC created 1965]

Return to EC 2.4.1 home page
Return to EC 2.4 home page
Return to EC 2 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page